VMware Horizon 7 is really end user friendly, you don't need to explain a lot about the application or the connections because there isn't a lot to explain there. Most of the application is self explanatory.
Horizon is really powerful, I'd recommend going with the Advanced license tho, just to get application streaming and virtual desktops.
The system was not too hard to set up, it took me a day to configure the connection server, the view agent server (RDS) and the security gateway. Review collected by and hosted on G2.com.