

Advarra eReg is a secure, paperless electronic Investigator Site File (eISF) system that integrates with Advarra's CTMSs--OnCore and Clinical Conductor. This centralized document management solution helps research sites improve productivity, accelerate study startup, and strengthen regulatory compliance through features such as streamlined document routing, real-time alerts for new documents, and electronic signature capabilities via Advarra eConsent. In addition to CTMS integration, Advarra eReg connects with Advarra’s CIRBI system, and internal site email systems to create a fully integrated research ecosystem. For sites transitioning to eReg, Advarra offers automated document migration, ensuring a seamless transfer of existing files and enabling immediate value from its connected technology platform.

OnCore CTMS is the trusted clinical trial management system (CTMS) used by nearly 90% of NCI-designated cancer centers and more than 90 of the top 125 academic medical centers. It streamlines operational, financial, and regulatory workflows to improve efficiency and quality across the research lifecycle. OnCore supports research sites and institutions with strong financial compliance through integrations with billing systems that enable end-to-end financial management. Deep EMR integrations provide seamless connectivity with widely used institutional systems. Additionally, advanced analytics deliver standardized, consistent reporting—including NCI reporting—offering clear visibility into a comprehensive set of metrics. OnCore also features exclusive, turnkey integrations with Advarra’s eReg and eSource systems, enhancing connectivity and driving greater efficiency across research workflows.

Clinical Conductor CTMS is an industry-leading clinical trial management system (CTMS) trusted by health systems, hospitals, site networks, and dedicated research sites. It streamlines operational, financial, and regulatory workflows to improve efficiency and quality across the research lifecycle. Backed by Advarra's expert team with deep experience in research operations, Clinical Conductor offers true enterprise capabilities that enable organizations to scale—supporting growth, high study volumes, and multi-site management. The platform delivers comprehensive, end-to-end functionality, including strong financial management workflow management, protocol management, participant recruitment, visit tracking, scheduling, and financial reporting. Clinical Conductor also features exclusive, turnkey integrations with Advarra’s eReg and eSource systems, enhancing connectivity and driving greater efficiency across research workflows.

Advarra eSource supports data capture and management for research sites, eliminating paper-based source documents and reducing duplicative, burdensome processes through integration with Advarra’s CTMS platforms, OnCore and Clinical Conductor. This enables sites to accelerate compliance, improve productivity and data quality, and streamline workflows between CTMS and source documentation systems. Organizations leveraging Advarra eSource also benefit from enhanced integrations with Advarra EDC, sponsor EDC systems, and site EMR platforms, creating a more connected and efficient data ecosystem.

CIRBI® is Advarra’s secure, proprietary platform that supports our gold-standard IRB process and is a single source of truth for submissions, required actions, study status, and board decisions. Built with intuitive dashboards, adaptive forms, and pre-populated data to accelerate startup and simplify ongoing submissions. CIRBI offers direct integration with Advarra’s eReg, sponsor eTMFs, and Advarra’s Study Collaboration solutions, to reduce administrative burden, shorten study startup, and strengthen document quality.

Advarra is a leading clinical research organization (CRO) specializing in providing comprehensive services for clinical trials across various therapeutic areas. With a focus on advancing medical research, Advarra offers expertise in study design, patient recruitment, and regulatory compliance. The organization is dedicated to supporting pharmaceutical, biotechnology, and medical device companies in bringing innovative treatments to market. Their commitment to quality and efficiency is reflected in their extensive experience and robust network of research sites. For more information, visit their website at [advarra.com](https://www.advarra.com/).