Nelson+ is a cloud-based data management system designed to support end-to-end workflows in low-dose CT lung cancer screening. The platform centralises all programme activities, including invitation management, eligibility assessment, pre-screening questionnaires, lung health checks, CT booking, reporting pathways, follow-up processes, and national data submissions. It is intended to provide a single environment where clinical, operational, and administrative steps can be monitored and documented consistently. The system enables structured data collection and workflow standardisation across screening hubs, hospitals, mobile CT units, and community diagnostic centres. Nelson+ offers role-based access control, full activity logging, and configurable workflows that align with clinical and operational requirements. All actions taken within the system are auditable, supporting quality assurance processes and compliance with screening standards. Nelson+ integrates with imaging systems, triage tools, electronic health record platforms, and national reporting frameworks. It supports secure data transfer, automated task progression, and real-time visibility of programme metrics. The platform is hosted in an NHS-approved cloud environment and adheres to recognised information governance and cybersecurity standards, including encryption, multi-layer access control, and compliance with NHS DCB0129 and DTAC requirements. The system is used to coordinate screening appointments, manage participant pathways, and facilitate communication with primary and secondary care. It is designed to reduce duplication of work, maintain data accuracy, and ensure that screening workflows can be delivered reliably at scale. Nelson+ is developed in collaboration with clinical and operational teams, with the aim of providing functionality that reflects real-world screening processes and supports consistent programme delivery.