Cleo is a neuroscience-based learning management system that helps educators build individualized learning experiences while simplifying lesson planning, scheduling, and grading. Its neuroscience-trained AI mentor helps students learn how to learn and acts as a 24/7 co-pilot for teachers. Leveraging purpose-designed AI to engineer] neuroscience principles directly into instruction, it drives measurably better outcomes across classrooms, bridging curriculum, achievement, and equity gaps. ​ Cleo has a Responsibly Designed AI certification issued by Digital Promise. It is a formal member of the UNESCO Global Alliance on the Science of Learning for Education and part of iRAISE (International Research-driven Alliance for AI Serving Every Child).​