OpenFreezer is an open-source laboratory information management system (LIMS) designed to streamline and organize laboratory workflows. It provides a platform for tracking various laboratory activities, including sample management, plasmid tracking, and experimental data logging. With a focus on improving efficiency and accuracy, OpenFreezer allows users to store, retrieve, and share information seamlessly within research environments. The system is highly customizable and can be adapted to meet the specific needs of different laboratories. The software is available for free, and its website, http://openfreezer.org/, offers additional resources and support for users.