Unfold AI

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Unfold AI is an FDA-cleared clinical decision support platform developed by Avenda Health to improve prostate cancer treatment planning. Using advanced artificial intelligence, Unfold AI precisely maps the location and extent of cancer within the prostate, enabling personalized, focal treatment strategies that preserve quality of life while reducing the risk of undertreatment. Clinical studies show that Unfold AI-guided treatments result in a 71% higher likelihood of being cancer-free compared to conventional methods. The platform helps urologists and oncologists avoid unnecessary damage to healthy tissue—minimizing urinary and sexual side effects—and improves confidence in treatment decisions by visualizing tumor geometry more accurately than standard imaging alone. Designed for both newly diagnosed patients and those seeking post-treatment evaluation, Unfold AI integrates seamlessly into clinical workflows, supporting individualized care without compromising cancer control.