Rayyan is an intelligent research collaboration platform designed to streamline the process of conducting literature and systematic reviews. Leveraging artificial intelligence, machine learning, and natural language processing, Rayyan assists researchers in efficiently screening and analyzing vast amounts of scholarly articles, significantly reducing the time and effort required to complete comprehensive reviews. Trusted by over 450,000 researchers worldwide, Rayyan offers a user-friendly interface that supports both individual and collaborative research endeavors. Key Features and Functionality: - AI-Powered Screening: Utilizes machine learning algorithms to understand language, learn from user decisions, and expedite the screening process by predicting article relevance. - Data Extraction: Provides tools to create custom extraction forms, capture structured data from PDFs, and track completion status, all within the platform. - PICO Highlighting and Filtering: Automatically identifies and highlights Population, Intervention, Comparison, and Outcome terms in articles, facilitating focused analysis. - Mobile Accessibility: Offers a mobile app that allows users to work on reviews anytime, anywhere, even offline, enhancing productivity on the go. - Collaborative Tools: Enables seamless collaboration among research teams with features like blinded data extraction, conflict resolution, and progress tracking. Primary Value and Problem Solved: Rayyan addresses the challenges of time-consuming and labor-intensive literature and systematic reviews by providing an AI-driven platform that automates and simplifies the screening and data extraction processes. By integrating advanced technologies and user-centric features, Rayyan empowers researchers to focus more on analysis and synthesis, thereby accelerating scientific and medical discoveries. Its collaborative capabilities ensure that research teams can work efficiently, maintain methodological rigor, and produce high-quality, evidence-based outcomes.