PubCompare is a research optimization platform focused on extracting and comparing experimental protocols from millions of scientific publications and patents. By navigating directly through the methods sections of documents, it allows researchers to easily identify subtle differences and select the most efficient protocols for their experiments. The platform features a topic-based search for quick access to relevant methodologies and a protocol comparator that showcases variations between similar set-ups. Designed for both academic and industrial scientists, PubCompare aims to minimize experimental errors, save on research costs, and enhance overall research quality. Available in free and premium models, it provides essential tools for precision-driven scientific inquiry.