If you use Quickbooks Desktop, and have employees, Payroll for Quickbooks Desktop is a must have. New payroll tax rates, forms, and topics are available for download frequently. I feel like we are always up to date and in compliance. All withholdings are automatically calculated and deducted from employees' paychecks. All liabilities are tracked on the payroll page, showing the date the remittance is due and the amount that is do. It is also easy to run reports of the liabilities due, along with other payroll data. Some liabilities are also available for epayment. For instance, I can pay the IRS directly through Quickbooks. Lastly, paying employees with direct deposit is very easy and accessible.
My only real criticism of Payroll for Quickbooks Desktop is that it is very expensive. There is a huge (and constantly growing) annual subscription fee. Plus there is a fee for each check that is direct deposited.
If you use Quickbooks Desktop, and are currently handling payroll manually, you should definitely use Payroll...if it isn't cost prohibitive.
Without Payroll for Quickbooks Desktop I would have to manually calculate all payroll taxes for each paycheck. Then I would have to manually keep track of cumulative totals, and manually prep all reports. This means a huge potential for making mistakes. There would also be no ability to direct deposit paychecks.