1. [Home](https://www.g2.com/)
2. ...
3. [Emerging AI Software](https://www.g2.com/categories/emerging-ai-software)
4. [Origami Therapeutics Discussions](https://www.g2.com/products/origami-therapeutics/discuss)

[
 ![Product Avatar Image](https://images.g2crowd.com/uploads/product/image/large_detail/large_detail_fc9e270fbaa8ae0141e4794add736681/origami-therapeutics.jpg "Product Avatar Image")
](/products/origami-therapeutics/reviews)

[

Origami Therapeutics

](/products/origami-therapeutics/reviews)

0 ratings

Origami Therapeutics is a preclinical-stage biopharmaceutical company dedicated to developing innovative small-molecule therapies for neurodegenerative diseases. Utilizing their proprietary ORICISION™ drug discovery platform, Origami focuses on creating protein degraders and conformation correctors that target and eliminate disease-causing proteins, aiming to modify disease progression and improve patient outcomes. Key Features and Functionality: - Protein Degradation: Origami's therapies are designed to selectively degrade and remove misfolded or toxic proteins implicated in neurodegenerative diseases, while preserving normal protein function. - Small-Molecule Therapeutics: The company develops orally administrable small molecules, ensuring broad distribution within the body and facilitating ease of manufacturing. - ORICISION™ Platform: This proprietary platform enables the discovery of both protein degraders and conformation correctors, allowing for tailored treatments based on patient-derived disease models. - Targeting "Undruggable" Proteins: Origami's approach addresses proteins traditionally considered "undruggable," expanding therapeutic possibilities for various neurodegenerative conditions. Primary Value and Problem Solved: Origami Therapeutics addresses the critical need for disease-modifying treatments in neurodegenerative disorders by targeting the root cause—misfolded or toxic proteins. Their innovative therapies aim to halt or slow disease progression, offering hope for improved quality of life for patients suffering from conditions like Huntington's disease, Alzheimer's disease, Parkinson's disease, amyotrophic lateral sclerosis (ALS), and frontotemporal dementia.

Show More

When users leave Origami Therapeutics reviews, G2 also collects common questions about the day-to-day use of Origami Therapeutics. These questions are then answered by our community of 850k professionals. Submit your question below and join in on the G2 Discussion.

* * *

### 0.0

Nps Score

### All Origami Therapeutics Discussions

Search

Most CommentedMost HelpfulCommon QuestionsNewest

All DiscussionsDiscussions with CommentsCommon QuestionsDiscussions without Comments

FilterFilter

Filter byExpand/Collapse 

Sort by

Most Commented

Most Helpful

Common Questions

Newest

Filter by

All Discussions

Discussions with Comments

Common Questions

Discussions without Comments

Sorry...

There are no questions about Origami Therapeutics yet.

## Start a New Software Discussion

Have a software question?

Get answers from real users and experts

[Start A Discussion](/products/origami-therapeutics/discussions/new?entry_point=discussions%23product)

* * *

 ![Product Avatar Image](https://images.g2crowd.com/uploads/product/image/thumb_square/thumb_square_fc9e270fbaa8ae0141e4794add736681/origami-therapeutics.jpg "Product Avatar Image")

### Have you used Origami Therapeutics before?

Answer a few questions to help the Origami Therapeutics community

[
Yes
](javascript:void(0))[
Yes
](https://www.g2.com/login?context=product_review&return_to=https%3A%2F%2Fwww.g2.com%2Fproducts%2Forigami-therapeutics%2Fdiscuss%3Fsmall_ask%3Dorigami-therapeutics)
No