---
title: OnCore CTMS Reviews
meta_title: 'OnCore CTMS Reviews 2026: Details, Pricing, & Features | G2'
meta_description: Filter 14 reviews by the users' company size, role or industry to
  find out how OnCore CTMS works for a business like yours.
aggregate_rating:
  rating_value: 4.4
  review_count: 14
  scale: '5'
date_modified: '2026-08-11'
parent_category:
  name: Clinical Research
  url: https://www.g2.com/categories/clinical-research
---


# OnCore CTMS Reviews
**Vendor:** Advarra  
**Category:** [Clinical Trial Management Systems](https://www.g2.com/categories/clinical-trial-management-systems)  
**Average Rating:** 4.4/5.0  
**Total Reviews:** 14
## About OnCore CTMS
OnCore CTMS is the trusted clinical trial management system (CTMS) used by nearly 90% of NCI-designated cancer centers and more than 90 of the top 125 academic medical centers. It streamlines operational, financial, and regulatory workflows to improve efficiency and quality across the research lifecycle. OnCore supports research sites and institutions with strong financial compliance through integrations with billing systems that enable end-to-end financial management. Deep EMR integrations provide seamless connectivity with widely used institutional systems. Additionally, advanced analytics deliver standardized, consistent reporting—including NCI reporting—offering clear visibility into a comprehensive set of metrics. OnCore also features exclusive, turnkey integrations with Advarra’s eReg and eSource systems, enhancing connectivity and driving greater efficiency across research workflows.




## OnCore CTMS Reviews
  ### 1. OnCore Streamlines Our Processes with an Intuitive UI and API

**Rating:** 4.0/5.0 stars

**Reviewed by:** Verified User in Hospital & Health Care | Enterprise (> 1000 emp.)

**Reviewed Date:** August 10, 2026

**What do you like best about OnCore CTMS?**

OnCore has helped our institution streamline many processes and serves as a true institutional CTMS. Its well-documented API and database have been especially valuable for facilitating communication and collaboration with our technical teams. As a vendor, Advarra maintains open communication with customers and actively listens to feedback, helping users feel heard and supported. The user interface is intuitive and easy to navigate while still providing the functionality needed to support our operations.

**What do you dislike about OnCore CTMS?**

The platform can be somewhat rigid, with limited opportunities for customization. While this consistency can be beneficial in promoting standardized processes, additional flexibility would be helpful, as each institution has unique workflows and operational needs. Allowing for more configuration options would enable organizations to better align the system with their specific processes while still maintaining overall standardization.

**What problems is OnCore CTMS solving and how is that benefiting you?**

OnCore's API and database accessibility enabled us to integrate with our EMR and establish efficient data-sharing processes across various institutional systems, improving interoperability and reducing manual effort. These capabilities have also allowed our institution to independently develop and maintain custom integrations and connections, giving us greater flexibility to support our evolving business and research needs.

  ### 2. OnCore Streamlines Clinical Trial Tracking with End-to-End Visibility

**Rating:** 4.0/5.0 stars

**Reviewed by:** Verified User in Research | Mid-Market (51-1000 emp.)

**Reviewed Date:** July 22, 2026

**What do you like best about OnCore CTMS?**

I like that OnCore provides a streamlined system for tracking clinical trials at our institution. It's user-friendly and allows visibility to different areas of the trial from accrual to payments.

**What do you dislike about OnCore CTMS?**

The system can look a little overwhelming at times since there are a lot of fields available that we don't use and aren't able to hide or eliminate. The way to associate procedures to visits in calendars can be a bit tedious as well.

**What problems is OnCore CTMS solving and how is that benefiting you?**

It's provided great visibility for reporting and metrics.

  ### 3. OnCore: Easy to Navigate and Great for Team Collaboration

**Rating:** 4.0/5.0 stars

**Reviewed by:** Verified User in Research | Mid-Market (51-1000 emp.)

**Reviewed Date:** May 29, 2026

**What do you like best about OnCore CTMS?**

I like that OnCore is an easy to navigate user-friendly system. It allows research teams to work in one location and fosters collaboration within teams.

**What do you dislike about OnCore CTMS?**

I feel at times there is functionality that could be added to enhance workflows.

**What problems is OnCore CTMS solving and how is that benefiting you?**

OnCore is streamlining workflows across our enterprise and creating consistency across research tasks.

  ### 4. A good software to handle clinical research

**Rating:** 4.0/5.0 stars

**Reviewed by:** Verified User in Research | Small-Business (50 or fewer emp.)

**Reviewed Date:** June 10, 2022

**What do you like best about OnCore CTMS?**

It is an excellent software for organizing clinical research. It helped us reduce duplicated data and control the budget/billing within the project. However, the best feature is the goal-driven dashboards that help visualize the information quickly.

**What do you dislike about OnCore CTMS?**

I believe it is not a problem with the software, but as a freelance researcher, I handle multiple projects, and just a fraction of them require clinical research software. I will probably prefer software that offers to manage several clinical and non-clinical projects.

**Recommendations to others considering OnCore CTMS:**

I haven't tried a lot of clinical research management software, but I use project management software on a daily basis, and compare to those, this has a 4/5 stars

**What problems is OnCore CTMS solving and how is that benefiting you?**

I helped organize a client's clinical trial research. It streamlines the process of managing the studies, which comes in handy when you have multiple ongoing studies.

  ### 5. OnCore for Clinical Trial Managment

**Rating:** 3.5/5.0 stars

**Reviewed by:** Kelli  A. | Tobacco Treatment Specialist, Enterprise (> 1000 emp.)

**Reviewed Date:** January 12, 2019

**What do you like best about OnCore CTMS?**

I liked that you can customize roles in the staff list, instead of just using preset defaults. The branching for task management, process tracking, and notifying the next signatory authority when it is time for them to completed their part is all very easy to navigate, saves a lot of effort in remembering to notify the next person to move things along. 

**What do you dislike about OnCore CTMS?**

I do not like that you cannot hide fields that are not of use to a particular study or research team. I think that there is a lot of room for improvement when it comes to the display logic and navigating through the pages could be made more consumer-intuitive. 

**Recommendations to others considering OnCore CTMS:**

Although I don't know much about the purchasing side of the equation, I do know that from the perspective of someone who had to use the platform daily, my number one piece of advice is to really utilize any training, including supplemental training that your organization offers. It's a fairly dynamic platform, but in order to help it help you, you've got to know all of the capabilities and how to navigate them for your specific role. 

**What problems is OnCore CTMS solving and how is that benefiting you?**

Although I no longer use OnCore in my current role, the organization I work for has continued to use it and expand its availability to other departments. It has helped streamline the process of protocol activation and also allows for excellent checks and balances between different stages of protocol activation, study submission, and client management. 

  ### 6. Excellent resource for researchers

**Rating:** 4.0/5.0 stars

**Reviewed by:** Terrill F. | Research Assistant, Higher Education, Enterprise (> 1000 emp.)

**Reviewed Date:** October 28, 2016

**What do you like best about OnCore CTMS?**

That patients on clinical trials calendar's can easily be viewed and manipulated if need be.

**What do you dislike about OnCore CTMS?**

Without the correct permission, you cannot make the necessary changes to a study.

**Recommendations to others considering OnCore CTMS:**

To allow administrators to make more changes to the program without having to pay more money.

**What problems is OnCore CTMS solving and how is that benefiting you?**

Preventing study coordinators from having to do double entry; typing participant information into both PowerTrials and OnCore.



- [View OnCore CTMS pricing details and edition comparison](https://www.g2.com/products/oncore-ctms/reviews?filters%5Bnps_score%5D%5B%5D=4&section=pricing&secure%5Bexpires_at%5D=2026-08-13+00%3A01%3A22+-0500&secure%5Bsession_id%5D=3f250feb-a27c-40c3-85c6-b71be25e1b93&secure%5Btoken%5D=c9eb11b97aeb8211b5e09565cdde0dac371800fc4d0d9b05c90bbe4bb1022140&format=llm_user)
## OnCore CTMS Integrations
  - [Epic](https://www.g2.com/products/epic/reviews)
  - [Oracle PeopleSoft](https://www.g2.com/products/oracle-peoplesoft/reviews)

## OnCore CTMS Features
**Operational Data**
- Site Management
- Participant Management
- Data Centralization
- Contact Management
- Real-Time Data
- Inventory Management
- Audit Management
- Calendar Management
- Financial Management
- Document Management
- User Management
- Clinical Study Management
- Workflow Management
- Compliance Management
- Forms Management

**Operational Performance**
- Project Management
- Documentation
- Reporting
- Milestones Management
- Ad hoc Reporting

**Additional Functionality**
- API
- Scheduling
- Randomization
- Digital Signature
- Role-Based Permissions
- Customizable Reports
- Data Verification
- EMR/EHR
- Document Imaging
- AI Copilot
- HIPAA Compliant
- Data Visualization
- Data Capture and Transfer
- Enrollments/Onboarding
- Reporting & Statistics
- Patient Monitoring
- Access Controls/Permissions
- Patient Recruiting
- Alerts/Notifications
- Activity Dashboard
- Third-Party Integrations
- Monitoring
- CRF Tracking
- 21 CFR Part 11 Compliance
- Double Data Entry
- Activity Tracking
- Progress Tracking
- Reminders
- Data Synchronization
- Data Import/Export
- Document Storage
- Generative AI
- Trial Design
- Customizable Forms
- Drag & Drop
- Audit Trail
- Real-Time Monitoring
- Electronic Data Capture

## Top OnCore CTMS Alternatives
  - [Rave CTMS](https://www.g2.com/products/rave-ctms/reviews) - 4.2/5.0 (19 reviews)
  - [Viedoc](https://www.g2.com/products/viedoc/reviews) - 4.5/5.0 (225 reviews)
  - [Clinical Research Suite](https://www.g2.com/products/clinical-research-suite/reviews) - 3.8/5.0 (204 reviews)

