--- title: MasterControl Quality Management System Reviews meta_title: 'MasterControl Quality Management System Reviews 2026: Details, Pricing, & Features | G2' meta_description: Filter 528 reviews by the users' company size, role or industry to find out how MasterControl Quality Management System works for a business like yours. aggregate_rating: rating_value: 4.3 review_count: 528 scale: '5' date_modified: '2026-08-11' parent_category: name: Environmental, Quality and Safety Management url: https://www.g2.com/categories/environmental-quality-and-safety-management --- # MasterControl Quality Management System Reviews **Vendor:** MasterControl **Category:** [Quality Management Systems (QMS)](https://www.g2.com/categories/quality-management-qms) **Average Rating:** 4.3/5.0 **Total Reviews:** 528 ## About MasterControl Quality Management System MasterControl Quality Excellence is the #1 Quality Management System (QMS) in life sciences. Built on an AI-driven platform, it enables life-sciences companies to enable flexible quality event management, simplified document management, and automated training management—that all work seamlessly together to close the loop on quality. Targeted primarily at quality professionals within the life sciences industry, MasterControl Qx serves a diverse range of organizations, from pharmaceuticals to biotechnology and medical devices. These industries often face stringent regulatory requirements and complex quality assurance processes. MasterControl Qx offers a centralized platform that integrates various quality management functions, allowing users to manage quality events, documentation, training, and audits seamlessly. This integration not only enhances operational efficiency but also ensures that organizations remain compliant with industry standards. One of the standout features of MasterControl Qx is its intelligent automation capabilities. By automating routine quality management tasks, organizations can reduce manual errors and free up valuable time for quality professionals to focus on more strategic initiatives. Additionally, the platform provides robust data insights that empower users to make informed decisions based on real-time information. This data-driven approach enhances the ability to identify trends, monitor compliance, and drive continuous improvement within quality processes. Furthermore, MasterControl Qx is designed to foster collaboration across departments and teams. The platform's connected nature allows for easy sharing of information and documentation, ensuring that all stakeholders are aligned and informed. This collaborative environment not only enhances communication but also supports a culture of quality throughout the organization. By utilizing MasterControl Qx, companies can create a more agile and responsive quality management system that adapts to changing regulatory landscapes and market demands. Overall, MasterControl Quality Excellence (Qx) stands out in the QMS category by providing a holistic solution tailored to the specific needs of the life sciences industry. Its combination of intelligent automation, robust data insights, and collaborative features positions it as a valuable tool for organizations striving to maintain high-quality standards while navigating the complexities of regulatory compliance. ## MasterControl Quality Management System Pros & Cons **What users like:** - Users appreciate the **ease of use** of MasterControl, benefiting from its intuitive interface and customizable features. (115 reviews) - Users value the **centralized document management** features of MasterControl, enhancing integration and user experience effectively. (87 reviews) - Users value the **user-friendly training integration** and centralized system for managing compliance and quality events effectively. (65 reviews) - Users value the **efficient document control** in MasterControl, appreciating easy access to documents and timely upgrades. (47 reviews) - Users appreciate the **customizable and user-friendly features** of MasterControl, facilitating efficient quality management processes. (44 reviews) - Users appreciate the **intuitive interface** of MasterControl Quality Management System, making documentation management efficient and effortless. (42 reviews) - QMS Management (40 reviews) - Users appreciate the **time-saving and efficient workflows** of MasterControl, enhancing their document management experience significantly. (35 reviews) - Customizability (30 reviews) - Integrations (30 reviews) **What users dislike:** - Users find the **interface not intuitive** , struggling with complex setups and unclear iconography affecting user experience. (43 reviews) - Users face a **steep learning curve** with MasterControl, particularly during initial setup and navigation between modules. (42 reviews) - Users find the **difficult usability** of MasterControl's system a challenge, particularly with report creation and workflow setup. (32 reviews) - Users struggle with the **not user-friendly interface** of MasterControl, finding navigation and search features cumbersome and challenging. (29 reviews) - Users find the **complex setup** challenging, requiring extensive training to effectively use MasterControl's capabilities. (27 reviews) - Users find the **learning difficulty** considerable, requiring extensive training to navigate the system effectively. (25 reviews) - Module Issues (25 reviews) - Complexity (24 reviews) - Users express concerns about **feature limitations** from using older software versions, impacting access to updates and support. (24 reviews) - Limited Customization (21 reviews) ## MasterControl Quality Management System Reviews ### 1. Genuinely the worst software ive used. **Rating:** 0.0/5.0 stars **Reviewed by:** Verified User in Medical Devices **Reviewed Date:** July 30, 2026 **What do you like best about MasterControl Quality Management System?** There is very little I like about this software. The only thing I like is that validations are pretty easy. **What do you dislike about MasterControl Quality Management System?** it's terrible software. sometimes it's so bad that you wonder if it's a joke. it's very expensive for trash software. the modules are basically garbage, nothing is interoperable, there are basic problems like columns are not working, data is almost impossible to harvest, it just sucks. **What problems is MasterControl Quality Management System solving and how is that benefiting you?** the only thing it helps with is that it's a central repository for controlled documents for us. everything else is bad. ### 2. Inflexible and Storage-Limited Despite an Out-of-the-Box Start **Rating:** 0.5/5.0 stars **Reviewed by:** Verified User in Pharmaceuticals | Mid-Market (51-1000 emp.) **Reviewed Date:** April 14, 2026 **What do you like best about MasterControl Quality Management System?** Mastercontrol provided an out of the box solution with standard configurations that gave the ability for a low effort implementation **What do you dislike about MasterControl Quality Management System?** Everything else. MasterControl was inflexible and had issues with the amount of storage we needed for our validation deliverables. We hit issues trying to parse out user roles as well **What problems is MasterControl Quality Management System solving and how is that benefiting you?** MasterControl was serving as our eTMF/document repository. ### 3. Outdated System **Rating:** 0.0/5.0 stars **Reviewed by:** Verified User in Medical Devices | Mid-Market (51-1000 emp.) **Reviewed Date:** November 08, 2023 **What do you like best about MasterControl Quality Management System?** None, I really dislike the system....... **What do you dislike about MasterControl Quality Management System?** This is an outdated system that requires little customization without paying for assistance. Additionally, the way the records are set up are very confusing and the search function is awful. **What problems is MasterControl Quality Management System solving and how is that benefiting you?** They are charging us $8700 to reset our training matrices and user roles. Not beneficial **Official Response from Cole Herman:** > Thank you for your feedback. We understand flexibility and customization are extremely important—as we continue to develop our solutions, this has been top of mind. We’d love to show you how we’ve taken that into account with our new Advanced Quality Event Management (AQEM) software that is releasing in January. Additionally, we’ve taken our customers’ feedback on the search functionality and recently released a new Enhanced Search that provides broader matches and a more traditional search experience. We’d love to walk you through that as well. Please contact your account representative so we can address your concerns and improve your overall experience. ### 4. Its has too many steps and is not user friendly. I would rather use Sharepoint. **Rating:** 0.0/5.0 stars **Reviewed by:** Verified User in Pharmaceuticals | Small-Business (50 or fewer emp.) **Reviewed Date:** August 22, 2023 **What do you like best about MasterControl Quality Management System?** I do not find it helpful. Its too many steps **What do you dislike about MasterControl Quality Management System?** Its not easy to use. There is no organization to it. **What problems is MasterControl Quality Management System solving and how is that benefiting you?** It has the purpose of holding the documents but It needs more structure, such as folder system. It has so many steps that it takes long just to upload a series of documents. ## MasterControl Quality Management System Discussions - [What is MasterControl Quality Management System used for?](https://www.g2.com/discussions/what-is-mastercontrol-quality-management-system-used-for) - 1 comment - [View MasterControl Quality Management System pricing details and edition comparison](https://www.g2.com/products/mastercontrol-quality-management-system/reviews?filters%5Bnps_score%5D%5B%5D=1§ion=pricing&secure%5Bexpires_at%5D=2026-08-13+11%3A14%3A50+-0500&secure%5Bsession_id%5D=ceaf8b05-f27c-401c-bf14-b83f9cee5998&secure%5Btoken%5D=bce1377c68f505253c5c8ef51008b1cde6b9b8a28da6d2095f9f3c7992d7d9cc&format=llm_user) ## MasterControl Quality Management System Integrations - [Elemental Machines](https://www.g2.com/products/elemental-machines/reviews) - [Labguru ELN LIMS](https://www.g2.com/products/labguru-eln-lims/reviews) ## MasterControl Quality Management System Features **Additional Functionality** - Incident Management - Real-Time Monitoring - Evidence Management - Risk Alerts - Reporting & Statistics - Third-Party Integrations - Workflow Management - Risk Analysis - Sarbanes-Oxley Compliance - Single Sign On - Compliance Management - Policy Management - Real-Time Reporting - Audit Trail - Assessment Management - HIPAA Compliant - Operational Risk Management - Document Storage - Enterprise Risk Management - Data Visualization - Configurable Workflow - Vendor Management - IT Risk Management - User Management - Issue Management - Internal Controls Management - AI Copilot - Environmental Compliance - Customizable Reports - Data Import/Export - Risk Management - API - Document Management - Risk Assessment - Activity Dashboard - Task Management - Audit Management - Generative AI - Governance - Corrective and Preventive Actions (CAPA) - Alerts/Notifications - FDA Compliance - Secure Data Storage - Approval Process Control - Version Control **Quality Management** - Design Controls - Audit Management - Supplier Network Management - Risk Management **Usability** - All-Employee Access - Supporting Documents - Two-Way Communication - Multi-Channel Communication **Nonconformance** - Conformance Records - CAPA - Change Management - Task Management - Policy Management - Document Management - Incident Management - Equipment Management - Audit Management - Workflow Management - Risk Management - Communications Management - Training Management - Maintenance Management - Complaint Management - Inspection Management - ISO Standards Management - Calibration Management - Compliance Management **Content Management** - Bulk Upload and Indexing - Document Tracking - Version Controlling - Search Engine - File Planning and Milestones - Real-Time Authoring and Collaboration - Content Workflows **Document Management** - Dossier Management - Tech Files - Submission Planning - Archiving **Generative AI** - AI Text Generation **Generative AI** - AI Text Summarization - AI Text Generation - Generative AI **Operational Risk Management** - Operational Risk Methodology - Operational Risk Classification - Operational Risk Identification **Agentic AI - Enterprise Content Management (ECM)** - Autonomous Task Execution - Natural Language Interaction - Decision Making **Additional Functionality** - Content Library - Access Controls/Permissions - AI Copilot - Information Governance - Drag & Drop - Collaboration Tools - Reporting/Analytics - Data Capture and Transfer - Indexing - Filtering - Electronic Signature - Version Control - Mobile Access - Document Storage - Generative AI - Approval Process Control - Single Sign On - Image Editing - Customizable Branding - Search/Filter - Tagging - Audit Trail - Document Review - Activity Tracking - Activity Dashboard - Archiving & Retention - Secure Data Storage - Configurable Workflow - SSL Security - Alerts/Notifications - Data Synchronization - Secure Login - Content Delivery - Two-Factor Authentication - Customizable Templates - Mobile Capture - Offline Access - Templates - File Sharing **Quality System** - Analytics & Reporting - Real-time Collaboration - Document Control - Quality Processes **Reporting** - Priority Case Alerts - Trend Analysis - Performance Monitoring - Social Media Monitoring **Quality system** - Document Control - Collaboration - Analytics and Reports - Supplier Quality Control - Statistical Process Control - Approval Process Control - Quality Control **Regulatory Compliance** - Dashboards and Reporting - TMF Reference Models - Inspection Readiness - Role Permissions **Product Management** - Audit Trails - Label Management - Live Dashboards - Collaborative Authoring - Product Information **Workflows - Audit Management** - Audit Trail - Recommendations - Collaboration Tools - Integrations - Audit Planning **Monitoring - IT Risk Management** - AI Monitoring **Business Resilience** - Business Continuity - Compliance Management - Incident Management - Policy Management **Risk Management** - Assessments - Operational Risk - Supplier Evaluation **Regulatory Affairs** - Automated Notifications - Post-Market Surveillance - Communication Tools - Regulatory Intelligence **Generative AI** - AI Text Generation - AI Text Summarization - Generative AI **Documentation - Audit Management** - Customizable Forms - Checklists **Agentic AI - IT Risk Management** - Autonomous Task Execution - Multi-step Planning **Additional Functionality** - Social Media Integration - Survey/Poll Management - Live Chat - Real-Time Reporting - Support Ticket Tracking - Knowledge Base Management - Customer Complaint Tracking - Real-Time Notifications - Case Management - API - Collaboration Tools - Customizable Templates - AI Copilot - Data Import/Export - Interaction Tracking - Service Level Agreement (SLA) Management - Audit Trail - Issue Management - Real-Time Updates - Corrective and Preventive Actions (CAPA) - Access Controls/Permissions - Self Service Portal - Multi-Channel Management - Third-Party Integrations - Canned Responses - Email Management - Customizable Forms - Surveys & Feedback - Activity Dashboard - Prioritization - Routing - Support Ticket Management - Widgets - Chat/Messaging - Alerts/Escalation - Activity Tracking - SSL Security - Workflow Management - Quality Assurance - Feedback Management - Issue Tracking - Customizable Branding - Tagging - Customer Service Analytics - Assignment Management - Email Templates - Customizable Reports - Reporting/Analytics - Reporting & Statistics - Forms Management **Inspection Management** - Templates - Workflows - Corrective Actions **Reporting & Analytics - Audit Management** - Activity Dashboard - Audit Performance - Industry Compliance - ISO Compliance - Environmental Compliance - AML Compliance - Sarbanes-Oxley Compliance - KYC Compliance - FDA Compliance - OSHA Compliance - Real-Time Data - Real-Time Analytics **Generative AI** - AI Tasks **Additional Functionality** - Mobile Access - Corrective and Preventive Actions (CAPA) - Issue Management - Document Management - Role-Based Permissions - Activity Tracking - Document Storage - Reporting & Statistics - Task Management - Workflow Management - Status Tracking - Monitoring - Data Visualization - Approval Process Control - Forms Management - Change Management - Risk Alerts - Asset Tracking - AI Copilot - API - Risk Analysis - Policy Management - Incident Management - Real-Time Reporting - Real-Time Notifications - Alerts/Notifications - Security Auditing - Compliance Management - Risk Assessment - Real-Time Monitoring - Version Control - Archiving & Retention - Alerts/Escalation - Customizable Reports - Compliance Tracking - Access Controls/Permissions - Certification Tracking - Surveys & Feedback - Digital Signature - HIPAA Compliant - Reminders **Compliance** - Permits - Certifications **File Management** - File Type Support - Metadata - OCR Scanning - Versioning - Collaboration - Document Assembly - Form Creation - Portals and Sites - Disposition - Search - Web Interface - Mobile Apps **Workflow** - Process Automation - Conditions - Activities - Records Management - Case Management - Template Management - Document Management - Metadata Management - Content Management - Workflow Management - Compliance Management - Digital Asset Management - Task Management - File Management - Forms Management - SEO Management - Audit Management - Website Management - User Management **Platform** - Internationalization - Performance and Reliability - Reporting and Auditing - System of Record Integration - APIs **Agentic AI - Operational Risk Management** - Proactive Assistance **Additional Functionality** - Scenario Planning - Activity Tracking - Prioritization - Audit Trail - Risk Scoring - Approval Process Control - Customizable Reports - Predictive Analytics - AI Copilot - Alerts/Notifications - Dashboard - Data Visualization - Risk Reporting - Version Control - Risk Assessment - Reminders - Risk Analysis - Real-Time Reporting - Corrective and Preventive Actions (CAPA) - API **Platform** - Integration - Security & Privacy - Mobile Access - Flexibility **Services** - Implementation - Training & Learning - Customer Support - Professional Services **Additional Functionality** - Defect Tracking - Electronic Signature - Reporting & Statistics - Activity Dashboard - Data Import/Export - Generative AI - Nonconformance Tracking - Surveys & Feedback - Access Controls/Permissions - API - AI Copilot - Alerts/Notifications - Real-Time Data ## Top MasterControl Quality Management System Alternatives - [Qualio](https://www.g2.com/products/qualio/reviews) - 4.4/5.0 (775 reviews) - [Octave Reliance (ETQ Reliance)](https://www.g2.com/products/octave-reliance-etq-reliance/reviews) - 4.3/5.0 (606 reviews) - [Arena PLM & QMS](https://www.g2.com/products/arena-plm-qms/reviews) - 4.2/5.0 (454 reviews)