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Direct-to-Digital Staining

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Direct-to-Digital Staining is PathScience’s approach to creating stain-like pathology images digitally from unstained tissue scans. In a traditional digital pathology workflow, tissue is usually chemically stained before it is scanned, viewed, managed, or analyzed. Direct-to-Digital Staining moves part of that process upstream by using imaging and machine learning techniques to generate H&E-style virtual stain images from unstained tissue. The approach is intended to support pathologist-centered review and pathology workflows, especially in areas such as dermatopathology and Mohs surgery where tissue visualization, turnaround time, and tissue preservation are important. Direct-to-Digital Staining is not autonomous diagnostic AI and is not intended to replace pathologists. It is an image-generation and workflow-support technology designed to create familiar, interpretable pathology images while reducing reliance on traditional chemical staining steps.

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