What is CRMdesk? CRMdesk is a very efficient web-based help desk software for knowledgebase management and customer support automation over the Internet. Why use CRMdesk? The system is deployed as a cost-effective hosted solution to manage and analyze all of your customer requests from a centralized location. Who uses CRMdesk? From small companies to large enterprises, from specific manufactures to vertical business integration, CRMdesk is scalable enough to grow with your business needs.