First, a disclaimer: I am a product/project manager, not an expert in CDNs and cloud hosting, so I cannot comment on deeply technical aspects of the Akamai ecosystem. But having used Akamai as a CDN on several highly-trafficked global websites, I have always had a good experience of Akamai as a robust, highly sophisticated system to ensure resilient global delivery.
I particularly appreciate the customer service provided from onboarding to operations, and the commitment to customer success. There is a structured process to take clients through the service, to ensure that configuration is managed correctly, and that all possible optimisations are adopted.
I have also found the Akamai online portal easy to use to execute simple configurations and purge the Akamai cache - simple enough for non-technical users such as myself to feel they have control over content appearing around the world.
I have had no specific problems with Akamai.
We use Akamai to deliver web content to large global audiences, taking the load off our origin servers and ensuring efficient, controlled content distribution.