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# Microsoft Defender for Office 365 vs Zix Email Threat Protection Comparison - What are their main differences?

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Microsoft Defender for...Zix Email Threat Protection[+ Add Product](#)

Reviews

**Microsoft Defender for Office 365** [

4.5/5(298)

](https://www.g2.com/products/microsoft-microsoft-defender-for-office-365/reviews#reviews)

**Zix Email Threat Protection** [

4.6/5(11)

](https://www.g2.com/products/zix-email-threat-protection/reviews#reviews)

Pricing

**Microsoft Defender for Office 365**
 **$2.00** 1 User Per Month · Microsoft Defender for Office Plan 1

**Zix Email Threat Protection**
No pricing available

**Pricing Insights**
from reviews

Time to Implement

**Microsoft Defender for Office 365**
2 months

Based on 10 responses

**Zix Email Threat Protection**
Not enough reviews yet

Return on Investment

**Microsoft Defender for Office 365**
14 months

Based on 7 responses

**Zix Email Threat Protection**
Not enough reviews yet

Perceived Cost

**Microsoft Defender for Office 365**
$$$$$

**Zix Email Threat Protection**
$$$$$

Average Discount

**Microsoft Defender for Office 365**
12%

**Zix Email Threat Protection**
Not enough reviews yet

Pros & Cons

**Microsoft Defender for Office 365**
[
Ease of Use (9)
](https://www.g2.com/products/microsoft-microsoft-defender-for-office-365/reviews?filters%5Bsentiment_snippet%5D=1426149&qs=pros-and-cons#reviews)[
Security (8)
](https://www.g2.com/products/microsoft-microsoft-defender-for-office-365/reviews?filters%5Bsentiment_snippet%5D=1425350&qs=pros-and-cons#reviews)[
Complexity (8)
](https://www.g2.com/products/microsoft-microsoft-defender-for-office-365/reviews?filters%5Bsentiment_snippet%5D=1424859&qs=pros-and-cons#reviews)[
False Positives (6)
](https://www.g2.com/products/microsoft-microsoft-defender-for-office-365/reviews?filters%5Bsentiment_snippet%5D=1426481&qs=pros-and-cons#reviews)

**Zix Email Threat Protection**
Not enough data

Integrations

**Microsoft Defender for Office 365**
[

 ![Product Avatar Image](https://images.g2crowd.com/uploads/product/image/large_detail/large_detail_e89d21750715f4646ed61c011b2917dc/adobe-acrobat.png "Product Avatar Image")

Adobe Acrobat

](https://www.g2.com/products/adobe-acrobat/reviews)[

 ![Product Avatar Image](https://images.g2crowd.com/uploads/product/image/large_detail/large_detail_ae5d46296d0f8afa0fd352fc44bf419d/microsoft365.png "Product Avatar Image")

Microsoft 365

](https://www.g2.com/products/microsoft365/reviews)[

 ![Product Avatar Image](https://images.g2crowd.com/uploads/product/image/large_detail/large_detail_790f5095f4e17577cead05669971b794/microsoft-onedrive-for-business.jpg "Product Avatar Image")

Microsoft OneDrive

](https://www.g2.com/products/microsoft-onedrive-for-business/reviews)[

 ![Product Avatar Image](https://images.g2crowd.com/uploads/product/image/large_detail/large_detail_69054bc7d40597b06fc3905720ccc914/microsoft-outlook.png "Product Avatar Image")

Outlook

](https://www.g2.com/products/microsoft-outlook/reviews)[
View all
](https://www.g2.com/products/microsoft-microsoft-defender-for-office-365/integrations)

**Zix Email Threat Protection**
Not enough data

Screenshots

**Microsoft Defender for Office 365**
 ![Microsoft Defender for Office 365 screenshot](https://images.g2crowd.com/cdn-cgi/image/width=600,height=600,fit=scale-down,format=auto,onerror=redirect,/https://images.g2crowd.com/uploads/attachment/file/1244899/MicrosoftTeams-image-_1_.png)

**Zix Email Threat Protection**
No screenshot available

Ratings

Meets Requirements

**Microsoft Defender for Office 365**

9.0

9.0231

**Zix Email Threat Protection**

9.1

9.19

Ease of Use

**Microsoft Defender for Office 365**

8.9

8.9234

**Zix Email Threat Protection**

9.1

9.19

Ease of Setup

**Microsoft Defender for Office 365**

8.7

8.7118

**Zix Email Threat Protection**

8.1

8.18

Ease of Admin

**Microsoft Defender for Office 365**

8.9

8.9100

**Zix Email Threat Protection**

9.0

9.08

Quality of Support

**Microsoft Defender for Office 365**

8.7

8.7225

**Zix Email Threat Protection**

8.9

8.99

Has the product been a good partner in doing business?

**Microsoft Defender for Office 365**

8.8

8.8101

**Zix Email Threat Protection**

9.0

9.08

Product Direction (% positive)

**Microsoft Defender for Office 365**

9.4

9.4222

**Zix Email Threat Protection**

8.7

8.79

Features

Cloud Email Security[Hide 14 FeaturesShow 14 Features](javascript:void(0);)

8.8

164

Not enough data

Administration

Intelligence Reporting

8.8(won by default)

148

|

Verified

Not enough data

Email Integration Suppor

9.0(won by default)

147

|

Verified

Not enough data

Access Management

8.8(won by default)

140

|

Verified

Not enough data

Data Loss Prevention

8.5(won by default)

140

|

Verified

Not enough data

Maintenance

Auditing

8.7(won by default)

138

|

Verified

Not enough data

Allow and block lists

8.8(won by default)

145

|

Verified

Not enough data

Compliance

8.8(won by default)

142

Not enough data

Archiving

8.6(won by default)

135

|

Verified

Not enough data

Security

Anti-Malware/Anti-Spam

9.0(won by default)

151

|

Verified

Not enough data

Encryption

8.9(won by default)

141

Not enough data

Quarantine

8.7(won by default)

145

|

Verified

Not enough data

Advanced Threat Protection (ATP)

9.0(won by default)

144

|

Verified

Not enough data

Anti-Phishing

9.0(won by default)

148

|

Verified

Not enough data

Account takeover prevention

8.7(won by default)

138

|

Verified

Not enough data

Intelligent Email Protection[Hide 12 FeaturesShow 12 Features](javascript:void(0);)

8.9

5

Not enough data

Administration

Email Clients

9.0(won by default)

5

Not enough data

Compliance

Not enough data

Not enough data

Intelligence Reporting

Not enough data

Not enough data

Role-Based Rules

Not enough data

Not enough data

Detection

Real-Time Detection

8.7(won by default)

5

Not enough data

Data Exfiltration Detection

Not enough data

Not enough data

Activity Monitoring

Not enough data

Not enough data

Protection

Spam Filtering

9.0(won by default)

5

Not enough data

Targeted Attack Prevention

Not enough data

Not enough data

Policy Enforcement

Not enough data

Not enough data

Agentic AI - Intelligent Email Protection

Autonomous Task Execution

Not enough data

Not enough data

Adaptive Learning

Not enough data

Not enough data

Email Anti-spam[Hide 54 FeaturesShow 54 Features](javascript:void(0);)

7.8

14

Not enough data

Agentic AI - Email Anti-spam Features

Autonomous Task Execution

8.1(won by default)

13

Not enough data

Proactive Assistance

7.4(won by default)

11

Not enough data

Additional Functionality

Phishing Protection

Not enough data

Not enough data

Data Recovery

Not enough data

Not enough data

Archiving & Retention

Not enough data

Not enough data

Backup and Recovery

Not enough data

Not enough data

Policy Management

Not enough data

Not enough data

Email Management

Not enough data

Not enough data

Data Loss Prevention

Not enough data

Not enough data

Single Sign On

Not enough data

Not enough data

Data Storage Management

Not enough data

Not enough data

Fraud Detection

Not enough data

Not enough data

Email Routing

Not enough data

Not enough data

Data Verification

Not enough data

Not enough data

Compliance Management

Not enough data

Not enough data

Filtering

Not enough data

Not enough data

Search/Filter

Not enough data

Not enough data

SURLB/URIBL Filtering

Not enough data

Not enough data

Security Auditing

Not enough data

Not enough data

Data Synchronization

Not enough data

Not enough data

Anti Virus

Not enough data

Not enough data

Risk Assessment

Not enough data

Not enough data

Greylisting

Not enough data

Not enough data

Audit Trail

Not enough data

Not enough data

Reporting/Analytics

Not enough data

Not enough data

Allow/Block List

Not enough data

Not enough data

Vulnerability Scanning

Not enough data

Not enough data

Active Directory Integration

Not enough data

Not enough data

Compression

Not enough data

Not enough data

Email Tracking

Not enough data

Not enough data

Encryption

Not enough data

Not enough data

Anti Spam

Not enough data

Not enough data

Disaster Recovery

Not enough data

Not enough data

AI Copilot

Not enough data

Not enough data

Tagging

Not enough data

Not enough data

Secure Data Storage

Not enough data

Not enough data

Activity Tracking

Not enough data

Not enough data

Spam Blocker

Not enough data

Not enough data

Microsoft Outlook Integration

Not enough data

Not enough data

Spam Analysis

Not enough data

Not enough data

API

Not enough data

Not enough data

Categorization/Grouping

Not enough data

Not enough data

Event Tracking

Not enough data

Not enough data

Inbox Management

Not enough data

Not enough data

Spam Detection

Not enough data

Not enough data

Authentication

Not enough data

Not enough data

Third-Party Integrations

Not enough data

Not enough data

Reporting & Statistics

Not enough data

Not enough data

Spam Quarantine

Not enough data

Not enough data

SSL Security

Not enough data

Not enough data

Generative AI

Not enough data

Not enough data

Data Retention Management

Not enough data

Not enough data

Access Controls/Permissions

Not enough data

Not enough data

Monitoring

Not enough data

Not enough data

Show 3 feature categories with incomplete data

Email Security[Hide 32 FeaturesShow 32 Features](javascript:void(0);)

Not enough data

Not enough data

Additional Functionality

Phishing Protection

Not enough data

Not enough data

Threat Response

Not enough data

Not enough data

Domain Check

Not enough data

Not enough data

Security Auditing

Not enough data

Not enough data

AI/Machine Learning

Not enough data

Not enough data

Third-Party Integrations

Not enough data

Not enough data

AI Copilot

Not enough data

Not enough data

Reporting/Analytics

Not enough data

Not enough data

Anomaly/Malware Detection

Not enough data

Not enough data

SURLB/URIBL Filtering

Not enough data

Not enough data

Activity Dashboard

Not enough data

Not enough data

Scheduled/Automated Reports

Not enough data

Not enough data

For MSPs

Not enough data

Not enough data

Whitelisting/Blacklisting

Not enough data

Not enough data

Fraud Detection

Not enough data

Not enough data

Spam Blocker

Not enough data

Not enough data

Spam Quarantine

Not enough data

Not enough data

API

Not enough data

Not enough data

Data Leak Prevention

Not enough data

Not enough data

Encryption

Not enough data

Not enough data

Audit Trail

Not enough data

Not enough data

Real-Time Monitoring

Not enough data

Not enough data

Spam Analysis

Not enough data

Not enough data

Policy Management

Not enough data

Not enough data

Alerts/Escalation

Not enough data

Not enough data

Email Management

Not enough data

Not enough data

Vulnerability Scanning

Not enough data

Not enough data

Generative AI

Not enough data

Not enough data

Threat Protection

Not enough data

Not enough data

Email Attachment Protection

Not enough data

Not enough data

Email Filtering

Not enough data

Not enough data

Two-Factor Authentication

Not enough data

Not enough data

Antivirus[Hide 43 FeaturesShow 43 Features](javascript:void(0);)

Not enough data

Not enough data

Generative AI

AI Text Generation

Not enough data

Not enough data

AI Text Summarization

Not enough data

Not enough data

Generative AI

Not enough data

Not enough data

Additional Functionality

Real-Time Monitoring

Not enough data

Not enough data

API

Not enough data

Not enough data

Threat Protection

Not enough data

Not enough data

Spam Blocker

Not enough data

Not enough data

Spam Quarantine

Not enough data

Not enough data

Real-time Alerts

Not enough data

Not enough data

Data Security

Not enough data

Not enough data

Incident Management

Not enough data

Not enough data

Remote Update/Installation

Not enough data

Not enough data

DDoS Protection

Not enough data

Not enough data

Automatic Scans

Not enough data

Not enough data

Vulnerability/Threat Prioritization

Not enough data

Not enough data

Real-Time Analytics

Not enough data

Not enough data

Endpoint Protection

Not enough data

Not enough data

Identity Theft Protection

Not enough data

Not enough data

Security Auditing

Not enough data

Not enough data

Virus Definition Update

Not enough data

Not enough data

VPN

Not enough data

Not enough data

Tracker Blocking

Not enough data

Not enough data

Data Loss Prevention

Not enough data

Not enough data

AI Copilot

Not enough data

Not enough data

Webcam Protection

Not enough data

Not enough data

Anomaly/Malware Detection

Not enough data

Not enough data

Third-Party Integrations

Not enough data

Not enough data

Access Controls/Permissions

Not enough data

Not enough data

Password Management

Not enough data

Not enough data

Phishing Protection

Not enough data

Not enough data

Email Attachment Protection

Not enough data

Not enough data

AI/Machine Learning

Not enough data

Not enough data

Reporting & Statistics

Not enough data

Not enough data

Network Security

Not enough data

Not enough data

Authentication

Not enough data

Not enough data

Threat Response

Not enough data

Not enough data

Activity Dashboard

Not enough data

Not enough data

Vulnerability Scanning

Not enough data

Not enough data

Backup and Recovery

Not enough data

Not enough data

Next-Generation Firewall

Not enough data

Not enough data

Application Security

Not enough data

Not enough data

Whitelisting/Blacklisting

Not enough data

Not enough data

Server Monitoring

Not enough data

Not enough data

Endpoint Protection[Hide 11 FeaturesShow 11 Features](javascript:void(0);)

Not enough data

Not enough data

System Control

Device Control

Not enough data

Not enough data

Web Control

Not enough data

Not enough data

Application Control

Not enough data

Not enough data

Asset Management

Not enough data

Not enough data

System Isolation

Not enough data

Not enough data

Vulnerability Prevention

Endpoint Intelligence

Not enough data

Not enough data

Firewall

Not enough data

Not enough data

Malware Detection

Not enough data

Not enough data

Security Management

Incident Reports

Not enough data

Not enough data

Security Validation

Not enough data

Not enough data

Compliance 

Not enough data

Not enough data

User Insights

Reviewers' Company Size

[![Microsoft Defender for Office 365](https://images.g2crowd.com/uploads/product/hd_favicon/a8a99a96fda235658139f710592f8a53/microsoft-microsoft-defender-for-office-365.svg "Microsoft Defender for Office 365")](https://www.g2.com/products/microsoft-microsoft-defender-for-office-365/reviews)

Microsoft Defender for Office 365

Small-Business(50 or fewer emp.)

25.9%

Mid-Market(51-1000 emp.)

37.9%

Enterprise(\> 1000 emp.)

36.2%

[![Zix Email Threat Protection](https://images.g2crowd.com/uploads/product/hd_favicon/551e4a9205c55898e9e888f46fa1d581/zix-email-threat-protection.svg "Zix Email Threat Protection")](https://www.g2.com/products/zix-email-threat-protection/reviews)

Zix Email Threat Protection

Small-Business(50 or fewer emp.)

36.4%

Mid-Market(51-1000 emp.)

45.5%

Enterprise(\> 1000 emp.)

18.2%

Small-Business

(50 or fewer emp.)

25.9%

36.4%

Mid-Market

(51-1000 emp.)

37.9%

45.5%

Enterprise

(\> 1000 emp.)

36.2%

18.2%

Reviewers' Industry

[![Microsoft Defender for Office 365](https://images.g2crowd.com/uploads/product/hd_favicon/a8a99a96fda235658139f710592f8a53/microsoft-microsoft-defender-for-office-365.svg "Microsoft Defender for Office 365")](https://www.g2.com/products/microsoft-microsoft-defender-for-office-365/reviews)
Microsoft Defender for Office 365

Information Technology and Services

25.7%

Computer & Network Security

12.5%

Computer Software

12.5%

Financial Services

5.4%

Accounting

2.9%

Other

41.1%

[![Zix Email Threat Protection](https://images.g2crowd.com/uploads/product/hd_favicon/551e4a9205c55898e9e888f46fa1d581/zix-email-threat-protection.svg "Zix Email Threat Protection")](https://www.g2.com/products/zix-email-threat-protection/reviews)
Zix Email Threat Protection

Financial Services

27.3%

Health, Wellness and Fitness

18.2%

Retail

9.1%

Pharmaceuticals

9.1%

Insurance

9.1%

Other

27.3%

Alternatives

**Microsoft Defender for Office 365 Alternatives**

 ![Proofpoint Core Email Protection](https://images.g2crowd.com/uploads/product/hd_favicon/8adf2eedd5616a9f5e200c4520f6d30d/proofpoint-core-email-protection.svg "Proofpoint Core Email Protection")

[
Proofpoint Core Email...
](/products/proofpoint-core-email-protection/reviews)

 ![SpamTitan Email Security](https://images.g2crowd.com/uploads/product/hd_favicon/1553620140/spamtitan-email-security.svg "SpamTitan Email Security")

[
SpamTitan Email Security
](/products/spamtitan-email-security/reviews)

 ![IRONSCALES](https://images.g2crowd.com/uploads/product/hd_favicon/06b1561b9d4413964954a7658e64f056/ironscales.svg "IRONSCALES")

[
IRONSCALES
](/products/ironscales/reviews)

 ![Symantec Email Security.Cloud](https://images.g2crowd.com/uploads/product/hd_favicon/7e0271a147c13a70a6587f9586b454a0/symantec-email-security-cloud.png "Symantec Email Security.Cloud")

[
Symantec Email Security.Cloud
](/products/symantec-email-security-cloud/reviews)

**Zix Email Threat Protection Alternatives**

 ![Mimecast Advanced Email Security](https://images.g2crowd.com/uploads/product/hd_favicon/4de3129d806e9580f2866c054f5a8591/mimecast-advanced-email-security.svg "Mimecast Advanced Email Security")

[
Mimecast Advanced Email...
](/products/mimecast-advanced-email-security/reviews)

 ![Proofpoint Core Email Protection](https://images.g2crowd.com/uploads/product/hd_favicon/8adf2eedd5616a9f5e200c4520f6d30d/proofpoint-core-email-protection.svg "Proofpoint Core Email Protection")

[
Proofpoint Core Email...
](/products/proofpoint-core-email-protection/reviews)

 ![ThreatDown](https://images.g2crowd.com/uploads/product/hd_favicon/28bf06470a2d1a33a2054aaa7af30d4c/threatdown.svg "ThreatDown")

[
ThreatDown
](/products/threatdown/reviews)

 ![CrowdStrike Falcon Endpoint Protection Platform](https://images.g2crowd.com/uploads/product/image/thumb_square/thumb_square_56db399f44b6fabb7c667f09bc770579/crowdstrike-falcon-endpoint-protection-platform.png "CrowdStrike Falcon Endpoint Protection Platform")

[
CrowdStrike Falcon Endpoint...
](/products/crowdstrike-falcon-endpoint-protection-platform/reviews)

## Microsoft Defender for Office 365 vs Zix Email Threat Protection

When assessing the two solutions, reviewers found Zix Email Threat Protection easier to use, administer, and do business with overall. However, reviewers preferred the ease of set up with Microsoft Defender for Office 365.

- Reviewers felt that Zix Email Threat Protection meets the needs of their business better than Microsoft Defender for Office 365.
- When comparing quality of ongoing product support, reviewers felt that Zix Email Threat Protection is the preferred option.
- For feature updates and roadmaps, our reviewers preferred the direction of Microsoft Defender for Office 365 over Zix Email Threat Protection.