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# Arena PLM & QMS vs MasterControl Quality Management System Comparison - What are their main differences?

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Arena PLM & QMSMasterControl[+ Add Product](#)

Pricing

**Arena PLM & QMS**
Free Trial

**Contact Us** · Arena PLM Launch

**MasterControl Quality Management System**
 **Contact Us** Per Year · Quality Excellence

**Pricing Insights**
from reviews

Time to Implement

**Arena PLM & QMS**
3 monthsFaster

Based on 20 responses

**MasterControl Quality Management System**
7 months

Based on 15 responses

Return on Investment

**Arena PLM & QMS**
16 months

Based on 13 responses

**MasterControl Quality Management System**
16 months

Based on 14 responses

Perceived Cost

**Arena PLM & QMS**
$$$$$

**MasterControl Quality Management System**
$$$$$

Average Discount

**Arena PLM & QMS**
20%8% more

**MasterControl Quality Management System**
12%

 ![Arena PLM & QMS](https://images.g2crowd.com/uploads/product/hd_favicon/08a5a9b57ded85f944279a72e01d11cb/arena-plm-qms.svg "Arena PLM & QMS")

 ![MasterControl Quality Management System](https://images.g2crowd.com/uploads/product/image/thumb_square/thumb_square_952e9aa4df0af1b0706297e2afcb725f/mastercontrol-quality-management-system.png "MasterControl Quality Management System")

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**Pros & Cons**
from reviews

**Arena PLM & QMS**
[
Ease of Use (35)
](https://www.g2.com/products/arena-plm-qms/reviews?filters%5Bsentiment_snippet%5D=1273084&qs=pros-and-cons#reviews)[
Document Management (17)
](https://www.g2.com/products/arena-plm-qms/reviews?filters%5Bsentiment_snippet%5D=1273121&qs=pros-and-cons#reviews)[
Feature Limitations (10)
](https://www.g2.com/products/arena-plm-qms/reviews?filters%5Bsentiment_snippet%5D=1272906&qs=pros-and-cons#reviews)[
Missing Features (10)
](https://www.g2.com/products/arena-plm-qms/reviews?filters%5Bsentiment_snippet%5D=1275247&qs=pros-and-cons#reviews)

**MasterControl Quality Management System**
[
Ease of Use (129)
](https://www.g2.com/products/mastercontrol-quality-management-system/reviews?filters%5Bsentiment_snippet%5D=1738271&qs=pros-and-cons#reviews)[
Document Management (96)
](https://www.g2.com/products/mastercontrol-quality-management-system/reviews?filters%5Bsentiment_snippet%5D=1737107&qs=pros-and-cons#reviews)[
Learning Curve (47)
](https://www.g2.com/products/mastercontrol-quality-management-system/reviews?filters%5Bsentiment_snippet%5D=1737232&qs=pros-and-cons#reviews)[
Not Intuitive (47)
](https://www.g2.com/products/mastercontrol-quality-management-system/reviews?filters%5Bsentiment_snippet%5D=1737803&qs=pros-and-cons#reviews)

Integrations

**Arena PLM & QMS**
[

 ![Product Avatar Image](https://images.g2crowd.com/uploads/product/image/large_detail/large_detail_9fee325af54b7164fb0726a552801492/acumatica.png "Product Avatar Image")

Acumatica

](https://www.g2.com/products/acumatica/reviews)[

 ![Product Avatar Image](https://images.g2crowd.com/uploads/product/image/large_detail/large_detail_b11664c0283c06478a0d137dde3e4ccc/cadtalk.jpg "Product Avatar Image")

CADTalk

](https://www.g2.com/products/cadtalk/reviews)[

 ![Product Avatar Image](https://images.g2crowd.com/uploads/product/image/large_detail/large_detail_22a85dbf8c16b06c18be73247d2850a3/cofactr.png "Product Avatar Image")

Cofactr

](https://www.g2.com/products/cofactr/reviews)[

 ![Product Avatar Image](https://images.g2crowd.com/uploads/product/image/large_detail/large_detail_89f5e6430a9e891ee95e5e5cd87d1f7c/expandable-erp.png "Product Avatar Image")

Expandable ERP

](https://www.g2.com/products/expandable-erp/reviews)[
View all
](https://www.g2.com/products/arena-plm-qms/integrations)

**MasterControl Quality Management System**
[

 ![Product Avatar Image](https://images.g2crowd.com/uploads/product/image/large_detail/large_detail_73e65ac99df620046769ab7c0388e836/elemental-machines.jpeg "Product Avatar Image")

Elemental Machines

](https://www.g2.com/products/elemental-machines/reviews)[

 ![Product Avatar Image](https://images.g2crowd.com/uploads/product/image/large_detail/large_detail_861660987a504a5345b908f048b5c070/labguru-eln-lims.png "Product Avatar Image")

Labguru ELN LIMS

](https://www.g2.com/products/labguru-eln-lims/reviews)[

 ![Product Avatar Image](https://images.g2crowd.com/uploads/product/image/large_detail/large_detail_51f0ac70fda48ca220f82654681f4f39/mastercontrol-manufacturing-excellence.png "Product Avatar Image")

MasterControl Manufacturing...

](https://www.g2.com/products/mastercontrol-manufacturing-excellence/reviews)[

 ![Product Avatar Image](https://images.g2crowd.com/uploads/product/image/large_detail/large_detail_cbdded440dd46c7dcb4debe3e10b5048/microsoft-sharepoint.png "Product Avatar Image")

Microsoft SharePoint

](https://www.g2.com/products/microsoft-sharepoint/reviews)[
View all
](https://www.g2.com/products/mastercontrol-quality-management-system/integrations)

Screenshots

**Arena PLM & QMS**
 ![Arena PLM & QMS screenshot](https://images.g2crowd.com/cdn-cgi/image/width=600,height=600,fit=scale-down,format=auto,onerror=redirect,/https://images.g2crowd.com/uploads/attachment/file/125343/SCI-BOM-Risk-Subview.jpg)

**MasterControl Quality Management System**
 ![MasterControl Quality Management System screenshot](https://images.g2crowd.com/cdn-cgi/image/width=600,height=600,fit=scale-down,format=auto,onerror=redirect,/https://images.g2crowd.com/uploads/attachment/file/1275807/Training.png)

**Ratings**
from reviews

Meets Requirements

**Arena PLM & QMS**

8.6

8.6429

**MasterControl Quality Management System**

8.6

8.6442

Ease of Use

**Arena PLM & QMS**

8.2

8.2436

**MasterControl Quality Management System**

7.8

7.8474

Ease of Setup

**Arena PLM & QMS**

8.1

8.1236

**MasterControl Quality Management System**

7.6

7.6343

Ease of Admin

**Arena PLM & QMS**

8.5

8.5148

**MasterControl Quality Management System**

8.1

8.1327

Quality of Support

**Arena PLM & QMS**

8.5

8.5360

**MasterControl Quality Management System**

8.6

8.6441

Has the product been a good partner in doing business?

**Arena PLM & QMS**

8.9

8.9148

**MasterControl Quality Management System**

8.8

8.8327

Product Direction (% positive)

**Arena PLM & QMS**

8.5

8.5418

**MasterControl Quality Management System**

9.2

9.2428

**Features**
ratings from reviews

Quality Management (QMS)

8.1

125

7.8

335

Medical QMS

8.2

92

7.2

77

Enterprise Content Management (ECM)

Not enough data

8.9

9

Electronic Trial Master File (eTMF)

Not enough data

8.2

7

Product Lifecycle Management (PLM)

7.8

257

Not enough data

Complaint Management

Not enough data

7.5

9

User Insights

**Reviewers' Company Size**

Small-Business(50 or fewer emp.)
26.2%

Mid-Market(51-1000 emp.)
57.2%

Enterprise(\> 1000 emp.)
16.6%

Small-Business(50 or fewer emp.)
26.2%

Mid-Market(51-1000 emp.)
57.2%

Enterprise(\> 1000 emp.)
16.6%

Small-Business(50 or fewer emp.)
9.8%

Mid-Market(51-1000 emp.)
64.7%

Enterprise(\> 1000 emp.)
25.5%

Small-Business(50 or fewer emp.)
9.8%

Mid-Market(51-1000 emp.)
64.7%

Enterprise(\> 1000 emp.)
25.5%

**Reviewers' Industry**

[![Arena PLM & QMS](https://images.g2crowd.com/uploads/product/hd_favicon/08a5a9b57ded85f944279a72e01d11cb/arena-plm-qms.svg "Arena PLM & QMS")](https://www.g2.com/products/arena-plm-qms/reviews)
Arena PLM & QMS

Medical Devices
34.6%

Electrical/Electronic Manufacturing
10.7%

Biotechnology
8.1%

Mechanical or Industrial Engineering
5.6%

Consumer Electronics
4.3%

Other
36.8%

[![MasterControl Quality Management System](https://images.g2crowd.com/uploads/product/image/thumb_square/thumb_square_952e9aa4df0af1b0706297e2afcb725f/mastercontrol-quality-management-system.png "MasterControl Quality Management System")](https://www.g2.com/products/mastercontrol-quality-management-system/reviews)
MasterControl Quality Management System

Pharmaceuticals
35.5%

Medical Devices
25.5%

Biotechnology
14.7%

Hospital & Health Care
4.9%

Manufacturing
4.0%

Other
15.5%

Alternatives

**Arena PLM & QMS Alternatives**

 ![Propel](https://images.g2crowd.com/uploads/product/hd_favicon/1537468252/propel-propel.svg "Propel")

[
Propel
](/products/propel-propel/reviews)

 ![Qualio](https://images.g2crowd.com/uploads/product/hd_favicon/989edd615dfb84f85af09d42b2a45a5a/qualio.svg "Qualio")

[
Qualio
](/products/qualio/reviews)

 ![Octave Reliance (ETQ Reliance)](https://images.g2crowd.com/uploads/product/hd_favicon/5941a9432ebe44facaf9413366486f4d/octave-reliance-etq-reliance.svg "Octave Reliance (ETQ Reliance)")

[
Octave Reliance (ETQ Reliance)
](/products/octave-reliance-etq-reliance/reviews)

 ![Greenlight Guru Quality Management System](https://images.g2crowd.com/uploads/product/hd_favicon/caf5a7b58c7e47e88697fba4c7304a53/greenlight-guru-quality-management-system.svg "Greenlight Guru Quality Management System")

[
Greenlight Guru Quality...
](/products/greenlight-guru-quality-management-system/reviews)

**MasterControl Quality Management System Alternatives**

 ![Qualio](https://images.g2crowd.com/uploads/product/hd_favicon/989edd615dfb84f85af09d42b2a45a5a/qualio.svg "Qualio")

[
Qualio
](/products/qualio/reviews)

 ![Octave Reliance (ETQ Reliance)](https://images.g2crowd.com/uploads/product/hd_favicon/5941a9432ebe44facaf9413366486f4d/octave-reliance-etq-reliance.svg "Octave Reliance (ETQ Reliance)")

[
Octave Reliance (ETQ Reliance)
](/products/octave-reliance-etq-reliance/reviews)

 ![Greenlight Guru Quality Management System](https://images.g2crowd.com/uploads/product/hd_favicon/caf5a7b58c7e47e88697fba4c7304a53/greenlight-guru-quality-management-system.svg "Greenlight Guru Quality Management System")

[
Greenlight Guru Quality...
](/products/greenlight-guru-quality-management-system/reviews)

 ![Ideagen Quality Management](https://images.g2crowd.com/uploads/product/hd_favicon/d67ce15286f9c05cdb20f2a33577949d/ideagen-quality-management.svg "Ideagen Quality Management")

[
Ideagen Quality Management
](/products/ideagen-quality-management/reviews)

## Arena PLM & QMS vs MasterControl FAQs

Generated using AI

Last updated: August 14, 2026

### What is the difference between Arena PLM & QMS vs MasterControl?

MasterControl stands out for its higher G2 rating and stronger reviewer-cited support, while Arena PLM & QMS is noted for its ease of use and setup.

| [Arena PLM & QMS](https://www.g2.com/products/arena-plm-qms/reviews) | [MasterControl](https://www.g2.com/products/mastercontrol-quality-management-system/reviews) |
| --- | --- |
| 4.2/5 (464 reviews) | 4.3/5 (528 reviews) |
| Mid-Market | Mid-Market |
| 8.1 | 7.6 |
| 8.5 | 8.6 |
| Ease of Use (35 all-time mentions) | Ease of Use (115 all-time mentions) |

### How do the pricing models of Arena PLM & QMS and MasterControl compare?

Reviewers consider MasterControl the stronger value, as reflected in its higher Price/Cost satisfaction score.

- **Arena PLM & QMS:** In recent reviews, many cite high cost as a drawback, especially for small companies, with several wishing for a more affordable, barebones version.
- **MasterControl:** Reviewers describe MasterControl as expensive, but satisfaction with value is higher, and the modular approach allows adding only needed features.
- **Switching reasons:** Recent Arena PLM & QMS reviewers mention cost as a reason for considering alternatives, while MasterControl reviewers highlight the ability to select modules as a value driver.

### What are the best alternatives to Arena PLM & QMS and MasterControl?

The top 3 alternatives to Arena PLM & QMS and MasterControl are Qualio, Propel, and Octave Reliance (ETQ Reliance).

| Product | G2 Rating (reviews) | Largest Segment | Pricing Insight | Top Reviewer-Cited Strength |
| --- | --- | --- | --- | --- |
| [Arena PLM & QMS](https://www.g2.com/products/arena-plm-qms/reviews) | 4.2/5 (464 reviews) | Mid-Market | High cost cited as a drawback in recent reviews | Ease of Use (35 all-time mentions) |
| [MasterControl](https://www.g2.com/products/mastercontrol-quality-management-system/reviews) | 4.3/5 (528 reviews) | Mid-Market | Expensive but modular, higher value satisfaction | Ease of Use (115 all-time mentions) |
| [Qualio](https://www.g2.com/products/qualio/reviews) | 4.4/5 (781 reviews) | Mid-Market | — | Quality Management |
| [Propel](https://www.g2.com/products/propel-propel/reviews) | 4.3/5 (146 reviews) | Mid-Market | — | Configurability |
| [Octave Reliance (ETQ Reliance)](https://www.g2.com/products/octave-reliance-etq-reliance/reviews) | 4.3/5 (624 reviews) | Enterprise | — | Enterprise-Grade Compliance |

### Which Product Lifecycle Management (PLM) features should I prioritize when comparing Arena PLM & QMS and MasterControl?

Buyers should prioritize Document Management, Workflow Automation, Integration Capabilities, Customizability, and Compliance Support when comparing Arena PLM & QMS and MasterControl.

- **Document Management:** Arena PLM & QMS (17 all-time mentions), MasterControl (87 all-time mentions)
- **Workflow Automation:** Arena PLM & QMS (Structured workflows cited in recent reviews), MasterControl (Automated routing and workflow, 40 all-time QMS Management mentions)
- **Integration Capabilities:** Arena PLM & QMS (SOLIDWORKS: 10 all-time mentions, Onshape: 5), MasterControl (Integrations: 30 all-time mentions)
- **Customizability:** Arena PLM & QMS (Configurable fields and processes cited in recent reviews), MasterControl (Customizability: 30 all-time mentions)
- **Compliance Support:** Arena PLM & QMS (Standards & Regulations feature), MasterControl (Audit readiness and compliance, 40 all-time QMS Management mentions)

### What are the pros and cons of Arena PLM & QMS vs MasterControl?

Arena PLM & QMS is strongest in ease of use, while MasterControl leads in document management and compliance features.

- **Arena PLM & QMS strengths:** Ease of Use (35 all-time mentions), intuitive interface, strong document management, and efficient BOM management.
- **Arena PLM & QMS trade-offs:** High cost for small companies, feature limitations (10 all-time mentions), and search functionality issues (7 all-time mentions).
- **MasterControl strengths:** Document Management (87 all-time mentions), training management (65), compliance and audit readiness, high customizability (30), and integrations (30).
- **MasterControl trade-offs:** Not intuitive for some users (43 all-time mentions), learning curve (42), high cost, and module complexity.

### Is Arena PLM & QMS or MasterControl better for small businesses?

Arena PLM & QMS is a better fit for small businesses based on reviewer sentiment and market segment alignment.

- **Arena PLM & QMS:** Largest segment is Mid-Market, but recent reviews from small companies highlight ease of setup and use, despite cost concerns.
- **MasterControl:** Largest segment is Mid-Market, and recent reviews note that high cost and modular pricing can be prohibitive for small businesses.

### Which Product Lifecycle Management (PLM) platform has better integrations?

MasterControl is favored for integrations, with more reviewer-cited integration mentions and broader tool coverage.

- **Arena PLM & QMS:** SOLIDWORKS (10 all-time mentions), Onshape (5 all-time mentions), with recent reviews noting limited open integrations and paywalls.
- **MasterControl:** Integrations (30 all-time mentions), with reviewers highlighting integration options and frequent updates to integration capabilities.

### How do Arena PLM & QMS and MasterControl compare on customer support?

MasterControl and Arena PLM & QMS are at parity on Quality of Support, with scores of 8.6 and 8.5 respectively, below the materiality threshold.

- **Arena PLM & QMS:** Reviewers describe support as responsive and helpful, with 9 all-time mentions, though some cite occasional delays and limited customization support.
- **MasterControl:** Reviewers highlight strong customer support (29 all-time mentions), structured training, and prompt issue resolution, with some noting slow response times for complex issues.

### Which is easier to implement, Arena PLM & QMS or MasterControl?

Arena PLM & QMS and MasterControl are at near-parity on Ease of Setup, with scores of 8.1 and 7.6, indicating similar implementation experiences.

- **Arena PLM & QMS:** Reviewers frequently cite quick and user-friendly setup, minimal IT overhead, and guided onboarding, though some mention a learning curve for advanced features.
- **MasterControl:** Reviewers describe setup as straightforward, especially with vendor support, but note that configuration and training are important for successful rollout, with some complexity for regulated industries.

### Which product has better Workflows?

MasterControl is favored for Workflows, with more reviewer-cited strengths and higher all-time mention counts for workflow-related features.

- **Arena PLM & QMS:** Structured workflows and traceability are cited in recent reviews, with 9 all-time Product Lifecycle Management mentions and 8 Tracking Efficiency mentions.
- **MasterControl:** Automated routing, electronic approvals, and workflow customization are highlighted in recent reviews, with 40 all-time QMS Management mentions and 44 Features mentions.