# Best Scientific Data Management Systems (SDMS) for Medium-Sized Businesses

## How Many Scientific Data Management Systems (SDMS) Products Does G2 Track?

**Total Products under this Category:** 90

### Category Stats (Aug 2026)

- **Average Rating:** 4.52/5 The average rating of products in this category, based on all submitted ratings

_Last updated: August 14, 2026_

## How Does G2 Rank Scientific Data Management Systems (SDMS) Products?

**Why You Can Trust G2's Software Rankings:**

- 30 Analysts and Data Experts
- 1,100+ Authentic Reviews
- 90+ Products
- Unbiased Rankings

G2's software rankings are built on verified user reviews, rigorous moderation, and a consistent research methodology maintained by a team of analysts and data experts. Each product is measured using the same transparent criteria, with no paid placement or vendor influence. While reviews reflect real user experiences, which can be subjective, they offer valuable insight into how software performs in the hands of professionals. Together, these inputs power the G2 Score, a standardized way to compare tools within every category.

## G2 Grid® for Scientific Data Management Systems (SDMS)
 ![G2 Grid® for Scientific Data Management Systems (SDMS) plotting products by satisfaction and market presence](https://www.g2.com/categories/scientific-data-management-system-sdms/grids.png?focus%5B%5D=12430&focus%5B%5D=94672&focus%5B%5D=12435&focus%5B%5D=49257)

Highlighted products: STARLIMS, Labguru ELN LIMS, Thermo Scientific SampleManager LIMS Software, and SciNote.

Underlying data: [Grid® JSON](https://www.g2.com/categories/scientific-data-management-system-sdms/grids.json?focus%5B%5D=starlims&focus%5B%5D=labguru-eln-lims&focus%5B%5D=thermo-scientific-samplemanager-lims-software&focus%5B%5D=scinote&segment=mid-market)

**Sponsored**

### Dotmatics

Dotmatics is a scientific R&D platform that combines ELN (electronic lab notebook), sample and sequence registration, inventory management, workflow automation, and scientific data search and analytics in one connected system. Dotmatics Luma extends this with a unified data layer that brings together instrument outputs, application data, and enterprise sources, then organizes it for analysis, visualization, and decision-making across biology, chemistry, and materials. Built for biopharma, CRO/CDMOs, and industrial R&D, Dotmatics helps teams replace disconnected point tools and spreadsheets with a governed system of record. Scientists can plan and capture experiments, track materials with full chain of custody, and connect results to the right samples, sequences, and studies so prior work is easy to find and reuse. Role-based permissions, audit trails, and compliance-ready controls support regulated workflows, while flexible integrations connect to existing lab and enterprise systems. With Luma-powered search and analytics, teams can compare candidates across assays, spot trends and outliers in complex datasets, reduce re-runs, and gain clear visibility into what’s progressing, what’s blocked, and what to advance next.

[Visit website](https://www.g2.com/external_clickthroughs/record?secure%5Bad_program%5D=ppc&secure%5Bad_slot%5D=category_product_list_llm&secure%5Bcategory_id%5D=2191&secure%5Bchosen_at%5D=2026-08-15T13%3A33%3A52Z&secure%5Bdisplayable_resource_id%5D=2191&secure%5Bdisplayable_resource_type%5D=Category&secure%5Bmedium%5D=sponsored&secure%5Bplacement_reason%5D=page_category&secure%5Bplacement_resource_ids%5D%5B%5D=2191&secure%5Bprioritized%5D=false&secure%5Bproduct_id%5D=1186690&secure%5Bresource_id%5D=2191&secure%5Bresource_type%5D=Category&secure%5Bsource_type%5D=category_page&secure%5Bsource_url%5D=https%3A%2F%2Fwww.g2.com%2Fcategories%2Fscientific-data-management-system-sdms%2Fmid-market&secure%5Btoken%5D=ad13413e2fa85ef2807cf071494136e7799fe1d03851ba3bb9d43bd6c12935eb&secure%5Burl%5D=https%3A%2F%2Fgo.dotmatics.com%2Fluma-platform&secure%5Burl_type%5D=custom_url)

### [STARLIMS](https://www.g2.com/products/starlims/reviews)

As a recognized leader in enterprise informatics solutions, STARLIMS is committed to providing quality products and services to over 1,100 customers across the globe. Found in over 2,000 laboratories, STARLIMS serves Life Sciences, Contract Development Manufacturing Organizations (CDMOs), Food & Beverage, Chemical, Agrochemical, Oil & Gas, Consumer Goods, Contract Testing, Public Health, and Clinical Diagnostics organizations. With a modern and intuitive R&D ELN incorporated into our portfolio, STARLIMS address the critical challenges customers face in finding an advanced platform that supports them from R&D through to commercialization.

**Average Rating:** 4.5/5.0

**Total Reviews:** 156

#### How Do G2 Users Rate STARLIMS?

- **Lab Systems Integration:** 8.8/10 (Category avg: 8.4/10)
- **Query and Search:** 8.9/10 (Category avg: 8.5/10)
- **Library Collections:** 8.4/10 (Category avg: 8.4/10)
- **Ease of Use:** 8.4/10 (Category avg: 8.7/10)

#### Who Is the Company Behind STARLIMS?

- **Seller:** [STARLIMS](https://www.g2.com/sellers/starlims)
- **Year Founded:** 1986
- **HQ Location:** Hollywood, Florida
- **Twitter:** @starlims\_lims  
77 Twitter followers
- **LinkedIn® Page:** [www.linkedin.com](https://www.g2.com/external_clickthroughs/record?secure%5Bsource_type%5D=product_profile&secure%5Btoken%5D=07ccb770bda2fcfe8e8f6f9b7a16604c5b0d49fee8aee39738859ea2b8092fc7&secure%5Burl%5D=https%3A%2F%2Fwww.linkedin.com%2Fcompany%2Fstarlims%2F&secure%5Burl_type%5D=linkedin_company_website)  
249 employees on LinkedIn®

#### Who Uses This Product?

- **Top Industries:** Pharmaceuticals, Biotechnology
- **Company Size:** 46% Large, 42% Medium

#### What Do G2 Reviewers Say About STARLIMS?

_AI-generated summary from verified user reviews_

##### Pros

- Users enjoy the **extensive customization options** of STARLIMS, enhancing their laboratory data management efficiency and effectiveness.
- Users appreciate the **ease of use** in controlling various actions and processes with STARLIMS.
- Users value the **easy integration** of STARLIMS with other products, enhancing laboratory efficiency and data management.
- Users value the **comprehensive modules** of STARLIMS, enhancing data management and simplifying complex laboratory workflows.
- Users value the **configuration ease** of STARLIMS, finding it simple to customize and integrate with other products.

##### Cons

- Users find STARLIMS has an **outdated system** with a crowded layout, hampering user-friendliness and customization.
- Users find the **poor usability** of STARLIMS frustrating due to its un-friendly UI and steep learning curve.
- Users find STARLIMS to have **difficult usability** , struggling with its complicated interface and lack of clear guidance.
- Users find the **user-friendliness of SDMS and ELN components lacking** , making troubleshooting and performance challenging.
- Users struggle with the **poor documentation** of STARLIMS, making it challenging to navigate its complex features.

#### What Are Recent G2 Reviews of STARLIMS?

**["LIMS is a robust platform with strong maintainability."](https://www.g2.com/survey_responses/starlims-review-12572067)**

**Rating:** 4.0/5.0 stars

_— ROY R._

[Read full review](https://www.g2.com/survey_responses/starlims-review-12572067)

**["Very good experience"](https://www.g2.com/survey_responses/starlims-review-12014169)**

**Rating:** 4.0/5.0 stars

_— Anne A._

[Read full review](https://www.g2.com/survey_responses/starlims-review-12014169)

#### What Are G2 Users Discussing About STARLIMS?

- [What is your experience with STARLIMS in managing laboratory information, and what needs improvement?](https://www.g2.com/discussions/what-is-your-experience-with-starlims-in-managing-laboratory-information-and-what-needs-improvement)

### [Labguru ELN LIMS](https://www.g2.com/products/labguru-eln-lims/reviews)

Labguru is a secure, cloud-based Electronic Lab Notebook (ELN), Laboratory Information Management System (LIMS), and informatics platform designed to assist users in managing and recording laboratory data and inventory effectively. This comprehensive solution caters to the needs of life science research and industry, providing tools that enhance the efficiency and organization of laboratory operations. The platform is particularly beneficial for a diverse range of users, including scientists in pharmaceutical companies, mid-sized firms, startups, universities, and research institutes. Labguru facilitates the design of experiments and workflows, allowing researchers to capture both structured and unstructured data seamlessly. By enabling project management and collaboration, Labguru supports teams in sharing their findings and insights, fostering a more integrated research environment. Key features of Labguru include customizable experiment templates and the integration of standard operating procedures (SOPs) and protocols. These functionalities are designed to enhance data quality and streamline workflows, ultimately leading to cost reductions in laboratory operations. The platform also offers molecular biology and chemistry tools, which are essential for researchers working in these fields. Furthermore, Labguru's automation capabilities provide insights into lab data, making it easier for users to optimize their processes and improve overall lab efficiency. Accessibility is another significant advantage of Labguru, as it is available on both desktop and mobile devices through the cloud. This flexibility allows scientists to access their data and manage their projects from anywhere, ensuring that they can work effectively regardless of their location. With over 120,000 scientists utilizing Labguru globally, the platform has proven its value across various sectors, from large pharmaceutical companies to innovative startups. Overall, Labguru stands out in the realm of laboratory management solutions by combining robust data management capabilities with user-friendly features. Its focus on enhancing collaboration, improving data quality, and providing valuable insights into laboratory operations makes it a vital tool for researchers aiming to advance their scientific endeavors.

**Average Rating:** 4.6/5.0

**Total Reviews:** 165

#### How Do G2 Users Rate Labguru ELN LIMS?

- **Lab Systems Integration:** 8.7/10 (Category avg: 8.4/10)
- **Query and Search:** 8.5/10 (Category avg: 8.5/10)
- **Library Collections:** 8.5/10 (Category avg: 8.4/10)
- **Ease of Use:** 8.4/10 (Category avg: 8.7/10)

#### Who Is the Company Behind Labguru ELN LIMS?

- **Seller:** [Cenevo](https://www.g2.com/sellers/cenevo)
- **Company Website:** www.titian.co.uk
- **Year Founded:** 1999
- **HQ Location:** London, England, United Kingdom
- **Twitter:** @TitianSoftware  
168 Twitter followers
- **LinkedIn® Page:** [uk.linkedin.com](https://www.g2.com/external_clickthroughs/record?secure%5Bsource_type%5D=product_profile&secure%5Btoken%5D=b79ee6e45dc1b769fd0b0811891ea12230d64c2104bc682012cdcdaa0810f1e1&secure%5Burl%5D=https%3A%2F%2Fuk.linkedin.com%2Fcompany%2Ftitian-software&secure%5Burl_type%5D=linkedin_company_website)  
85 employees on LinkedIn®

#### Who Uses This Product?

- **Top Industries:** Biotechnology, Research
- **Company Size:** 75% Small, 19% Medium

#### What Do G2 Reviewers Say About Labguru ELN LIMS?

_AI-generated summary from verified user reviews_

##### Pros

- Users value the **excellent customer support** of Labguru ELN LIMS, enhancing usability and overall experience for startups.
- Users find Labguru ELN LIMS to be **intuitive and easy to use** , enhancing organization and collaboration effortlessly.
- Users value the **effective inventory management** of Labguru ELN LIMS, finding it essential for reducing waste and improving efficiency.
- Users value the **intuitive and reliable management** provided by Labguru, enhancing organization and compliance for scaling startups.
- Users value the **intuitive organization** capabilities of Labguru, enhancing efficiency and compliance in lab management.

##### Cons

- Users note the **limited functionality** in Labguru ELN LIMS, particularly for customizations and advanced analytical tools.
- Users experience **slow performance** with Labguru ELN LIMS, facing lag and long loading times that hinder productivity.
- Users face **difficult usability** challenges with Labguru ELN LIMS, struggling with navigation and section management features.
- Users face **data management issues** with Labguru ELN LIMS, including bugs, slow loading times, and incomplete functionality.
- Users find **limited customization** options in Labguru ELN LIMS, impacting usability and advanced data handling capabilities.

#### What Are Recent G2 Reviews of Labguru ELN LIMS?

**["Excellent electric notebook"](https://www.g2.com/survey_responses/labguru-eln-lims-review-8391717)**

**Rating:** 5.0/5.0 stars

_— Beibei L._

[Read full review](https://www.g2.com/survey_responses/labguru-eln-lims-review-8391717)

**["Customisable, Intuitive Interfaces with Dashboards and Powerful Workflow Automation"](https://www.g2.com/survey_responses/labguru-eln-lims-review-12258308)**

**Rating:** 4.0/5.0 stars

_— Matthew C._

[Read full review](https://www.g2.com/survey_responses/labguru-eln-lims-review-12258308)

#### What Are G2 Users Discussing About Labguru ELN LIMS?

- [How has Labguru supported your lab management, and what features do you find most valuable?](https://www.g2.com/discussions/how-has-labguru-supported-your-lab-management-and-what-features-do-you-find-most-valuable)
- [What is LIMS and its types?](https://www.g2.com/discussions/what-is-lims-and-its-types)
- [How do you use labguru?](https://www.g2.com/discussions/how-do-you-use-labguru)
- [Is labguru a LIMS?](https://www.g2.com/discussions/is-labguru-a-lims) - 1 comment
- [How much does labguru cost?](https://www.g2.com/discussions/how-much-does-labguru-cost)

### [Thermo Scientific SampleManager LIMS Software](https://www.g2.com/products/thermo-scientific-samplemanager-lims-software/reviews)

Thermo Scientific SampleManager LIMS, SDMS, ELN and LES Software manages your laboratory, data and procedural workflows, connecting with other enterprise systems, instruments, equipment and your customers to deliver increased compliance and productivity across your business. SampleManager LIMS software is a complete, comprehensive solution for lab, data and process management, and one of the most widely deployed LIMS in the world. For over 35 years, SampleManager LIMS software has supported customers using the latest technologies and is developed, designed and supported in an ISO 9001 environment. Through configuration, not customization, SampleManager LIMS software can be tailored to your specific business processes and laboratory workflows.

**Average Rating:** 4.3/5.0

**Total Reviews:** 108

#### How Do G2 Users Rate Thermo Scientific SampleManager LIMS Software?

- **Lab Systems Integration:** 8.9/10 (Category avg: 8.4/10)
- **Query and Search:** 9.3/10 (Category avg: 8.5/10)
- **Library Collections:** 8.8/10 (Category avg: 8.4/10)
- **Ease of Use:** 8.4/10 (Category avg: 8.7/10)

#### Who Is the Company Behind Thermo Scientific SampleManager LIMS Software?

- **Seller:** [Thermo Fisher Scientific](https://www.g2.com/sellers/thermo-fisher-scientific)
- **HQ Location:** Waltham, MA
- **Twitter:** @thermosci  
23,517 Twitter followers
- **LinkedIn® Page:** [www.linkedin.com](https://www.g2.com/external_clickthroughs/record?secure%5Bsource_type%5D=product_profile&secure%5Btoken%5D=6484afb965d2d2a1d069080518f41101e7e31d64e297398f95d7bdd5736ff5db&secure%5Burl%5D=https%3A%2F%2Fwww.linkedin.com%2Fcompany%2F3081%2F&secure%5Burl_type%5D=linkedin_company_website)  
100,255 employees on LinkedIn®
- **Ownership:** BMV:TMO
- **Total Revenue (USD mm):** $32,218

#### Who Uses This Product?

- **Top Industries:** Pharmaceuticals, Oil & Energy
- **Company Size:** 35% Medium, 33% Large

#### What Are Recent G2 Reviews of Thermo Scientific SampleManager LIMS Software?

**["Secure and complies with reuglatory"](https://www.g2.com/survey_responses/thermo-scientific-samplemanager-lims-software-review-6886210)**

**Rating:** 5.0/5.0 stars

_— Santosh P._

[Read full review](https://www.g2.com/survey_responses/thermo-scientific-samplemanager-lims-software-review-6886210)

**["I like the mobile-tablet to software connection partof software"](https://www.g2.com/survey_responses/thermo-scientific-samplemanager-lims-software-review-9848616)**

**Rating:** 4.0/5.0 stars

_— Vanaraj R._

[Read full review](https://www.g2.com/survey_responses/thermo-scientific-samplemanager-lims-software-review-9848616)

#### What Are G2 Users Discussing About Thermo Scientific SampleManager LIMS Software?

- [What do you recommend for those looking to replace Thermo Scientific SampleManager LIMS with another laboratory information management system?](https://www.g2.com/discussions/what-do-you-recommend-for-those-looking-to-replace-thermo-scientific-samplemanager-lims-with-another-laboratory-information-management-system)
- [What is Watson LIMS?](https://www.g2.com/discussions/what-is-watson-lims) - 2 comments
- [What is LIMS software in pharma?](https://www.g2.com/discussions/what-is-lims-software-in-pharma) - 1 comment
- [What are the unique features of LIMS?](https://www.g2.com/discussions/thermo-scientific-samplemanager-lims-software-what-are-the-unique-features-of-lims) - 1 comment
- [What is SampleManager LIMS?](https://www.g2.com/discussions/what-is-samplemanager-lims) - 1 comment

### [SciNote](https://www.g2.com/products/scinote/reviews)

SciNote is a leading locally installed or cloud-based Laboratory management system with: Electronic Lab Notebook (ELN), Lab Information Management System (LIMS) and laboratory data management features, designed to support scientists, lab teams, and research organizations in managing, organizing, and protecting scientific data. Founded in 2015, SciNote is headquartered in Middleton, Wisconsin, USA, with offices in Europe and a global customer base spanning over 100 countries. The platform is trusted by more than 100,000 scientists and renowned institutions such as the FDA, USDA, and the European Commission. Key Features of SciNote: - Electronic Lab Notebook (ELN): Intuitive experiment planning and data documentation - Inventory & Sample Tracking: Organize and trace reagents, materials, and samples - SOP & Protocol Management: Standardized, version-controlled workflows - Compliance-Ready Infrastructure: Built to support 21 CFR Part 11, GxP, and ISO 27001 standards - Project & Task Management: Centralize team activities and deadlines across research programs - User Roles & Permissions: Role-based access control for secure collaboration - API & Integration: RESTful API and interoperability with instruments, LIMS, and analytics platforms - Data Security: Encrypted cloud hosting with full audit trails and activity logs What SciNote Solves: SciNote solves the complexity of managing scientific workflows, fragmented documentation, and disconnected teams by offering one unified platform that brings clarity, consistency, and compliance to research environments. It replaces paper notebooks and spreadsheets with structured digital records that help: Reduce time spent on repetitive documentation Improve collaboration across lab teams and departments Maintain audit-ready compliance with regulatory standards Protect institutional knowledge and intellectual property Accelerate research workflows and data-driven decision-making Whether you're in biotech, pharma, medtech, diagnostics, agritech, CRO/CDMO services, or academic and government research, SciNote provides a scalable solution to modernize lab operations while ensuring scientific and regulatory integrity. Learn more at https://www.scinote.net

**Average Rating:** 4.2/5.0

**Total Reviews:** 303

#### How Do G2 Users Rate SciNote?

- **Lab Systems Integration:** 7.6/10 (Category avg: 8.4/10)
- **Query and Search:** 7.8/10 (Category avg: 8.5/10)
- **Library Collections:** 7.7/10 (Category avg: 8.4/10)
- **Ease of Use:** 7.9/10 (Category avg: 8.7/10)

#### Who Is the Company Behind SciNote?

- **Seller:** [SciNote](https://www.g2.com/sellers/scinote)
- **Company Website:** scinote.net
- **Year Founded:** 2015
- **HQ Location:** Middleton, WI
- **Twitter:** @scinoteELN  
1,971 Twitter followers
- **LinkedIn® Page:** [www.linkedin.com](https://www.g2.com/external_clickthroughs/record?secure%5Bsource_type%5D=product_profile&secure%5Btoken%5D=2644bd335f4f5d7b0b1d06de9204a795b22ea329b51e02498dc56a34742cd6cc&secure%5Burl%5D=https%3A%2F%2Fwww.linkedin.com%2Fcompany%2F10227272%2F&secure%5Burl_type%5D=linkedin_company_website)  
31 employees on LinkedIn®

#### Who Uses This Product?

- **Who Uses This:** Research Associate, Scientist
- **Top Industries:** Biotechnology, Research
- **Company Size:** 75% Small, 17% Medium

#### What Do G2 Reviewers Say About SciNote?

_AI-generated summary from verified user reviews_

##### Pros

- Users value the **ease of use** in SciNote, streamlining lab work and enhancing workflow efficiency.
- Users highlight the **effective organization** and integration capabilities of SciNote, enhancing efficiency and communication.
- Users benefit from the **exceptional organization efficiency** of SciNote, enabling easy tracing and integration of tasks.
- Users value the **team collaboration features** of SciNote, enhancing communication and efficiency in research projects.
- Users value the **highly effective and customizable inventory management** in SciNote, facilitating smooth operations and documentation.

##### Cons

- Users struggle with **data management issues** in SciNote, finding it inflexible and lacking essential features for seamless operation.
- Users find the **limited functionality** of SciNote frustrating, especially with its lack of advanced features for chemistry labs.
- Users find navigating tasks on SciNote to be **difficult and cumbersome** , hindering their overall efficiency and productivity.
- Users struggle with **navigation issues** in SciNote, facing challenges that initially hinder easy access to tools.
- Users find **difficult navigation** in SciNote frustrating, making it hard to fully utilize the available tools.

#### What Are Recent G2 Reviews of SciNote?

**["Helpful Platform with Exceptional Support"](https://www.g2.com/survey_responses/scinote-review-8770026)**

**Rating:** 4.0/5.0 stars

_— Verified User in Biotechnology_

[Read full review](https://www.g2.com/survey_responses/scinote-review-8770026)

**["Scinote Streamlined Our R&D Collaboration and eQMS Integration"](https://www.g2.com/survey_responses/scinote-review-12785249)**

**Rating:** 4.0/5.0 stars

_— Verified User in Biotechnology_

[Read full review](https://www.g2.com/survey_responses/scinote-review-12785249)

#### What Are G2 Users Discussing About SciNote?

- [What does Scinote do?](https://www.g2.com/discussions/what-does-scinote-do) - 1 comment
- [What is ELN software?](https://www.g2.com/discussions/what-is-eln-software) - 1 comment
- [How do you use Scinote?](https://www.g2.com/discussions/how-do-you-use-scinote) - 1 comment
- [How much does scinote cost?](https://www.g2.com/discussions/how-much-does-scinote-cost) - 1 comment

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Similar Categories

- [Electronic Lab Notebook (ELN)](/categories/electronic-lab-notebook-eln)
- [Lab Inventory Management](/categories/lab-inventory-management)

- [LIMS](/categories/lims)
- [Other Laboratory](/categories/other-laboratory)

[Browse Scientific Data Management System (SDMS) Themes](/categories/scientific-data-management-system-sdms/themes)