# Highest-Rated Electronic Trial Master File (eTMF) Software by G2 Users Check out this list of the highest-rated Electronic Trial Master File (eTMF) Software for your business, based on user satisfaction. A product's satisfaction score is calculated by a[proprietary algorithm](https://sell.g2.com/g2-scoring-methodologies)that factors in real-user satisfaction ratings from review data. Compare these top-rated products according to their satisfaction scores to streamline your buying process and quickly identify the most recommended solutions trusted by your peers. 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All SegmentsEnterprise ( \>1000 emp.)Mid-Market (51-1000 emp.)Small Business (50 or fewer emp.)All RegionsNorth America Highest-Rated Electronic Trial Master File (eTMF) Software by G2 Users [![linkedin](/assets/social-logos/linkedin-afe65e46604a5bd5105ab9c856116204040b6b3f2b2d42562fc8071ca0c48ca0.svg "linkedin")](https://www.linkedin.com/shareArticle?mini=true&summary=Compare+the+highest-rated+Electronic+Trial+Master+File+%28eTMF%29+Software+software+in+2026.+Find+the+best+platforms+ranked+by+verified+G2+user+ratings%2C+features%2C+and+real-world+reviews.&title=Highest+Rated+Electronic+Trial+Master+File+%28eTMF%29+Software+in+2026+%7C+G2&url=https%3A%2F%2Fwww.g2.com%2Fcategories%2Felectronic-trial-master-file-etmf%3Ftab%3Dhighest_rated) [![twitter](/assets/social-logos/twitter-61aaec80434c71387b8f7326e480592eae71c0a65afd051d66fce9b75a9bf417.svg "twitter")](https://twitter.com/intent/tweet?text=Highest+Rated+Electronic+Trial+Master+File+%28eTMF%29+Software+in+2026+%7C+G2&url=https%3A%2F%2Fwww.g2.com%2Fcategories%2Felectronic-trial-master-file-etmf%3Ftab%3Dhighest_rated&via=G2dotcom) [![facebook](/assets/social-logos/facebook-350d0b410d6b10debcf893050e803a8633d53561aa42807b087b8daf9be3668f.svg "facebook")](https://www.facebook.com/sharer/sharer.php?u=https%3A%2F%2Fwww.g2.com%2Fcategories%2Felectronic-trial-master-file-etmf%3Ftab%3Dhighest_rated) [![gmail](/assets/social-logos/gmail-6db42f21e7c254fae201b112bef0dd15d25223a5cbb32691ce80eab43761eadf.svg "gmail")](https://mail.google.com/mail/?view=cm&fs=1&tf=1&to=&su=Highest+Rated+Electronic+Trial+Master+File+%28eTMF%29+Software+in+2026+%7C+G2&body=https%3A%2F%2Fwww.g2.com%2Fcategories%2Felectronic-trial-master-file-etmf%3Ftab%3Dhighest_rated%0aCompare+the+highest-rated+Electronic+Trial+Master+File+%28eTMF%29+Software+software+in+2026.+Find+the+best+platforms+ranked+by+verified+G2+user+ratings%2C+features%2C+and+real-world+reviews.) [![mail](/assets/social-logos/mail-d55c53b04bf49872e40cd2443b85a99caa23394e6cf154ae32a9d08377c15d86.svg "mail")](mailto:?subject=Highest+Rated+Electronic+Trial+Master+File+%28eTMF%29+Software+in+2026+%7C+G2&body=https%3A%2F%2Fwww.g2.com%2Fcategories%2Felectronic-trial-master-file-etmf%3Ftab%3Dhighest_rated%0aCompare+the+highest-rated+Electronic+Trial+Master+File+%28eTMF%29+Software+software+in+2026.+Find+the+best+platforms+ranked+by+verified+G2+user+ratings%2C+features%2C+and+real-world+reviews.) ![copy_link](/assets/social-logos/copy_link-05d8dc5dc8576fc78425ad34d07241b060878835e555a30417ff41c18335e575.svg "copy\_link") All SegmentsEnterprise ( \>1000 emp.)Mid-Market (51-1000 emp.)Small Business (50 or fewer emp.)All RegionsNorth America [Collapse AllExpand All](#) G2 Satisfaction Score Information Compare [Expand/Collapse MasterControl Quality Management System](#) #1 [![MasterControl Quality Management System](https://images.g2crowd.com/uploads/product/image/thumb_square/thumb_square_952e9aa4df0af1b0706297e2afcb725f/mastercontrol-quality-management-system.png)](/products/mastercontrol-quality-management-system/reviews) [MasterControl Quality Management System](/products/mastercontrol-quality-management-system/reviews "MasterControl Quality Management System") 92 [Expand/Collapse MasterControl Quality Management System](#) Overall Satisfaction Score 92 Top Industries of Reviewers: Pharmaceuticals 41% Medical Devices 31% Biotechnology 20% Hospital & Health Care 8% Ratings from Reviews (out of 10): Ease of Use Average: 9.1 8.0 Meets Requirements Average: 9.4 8.9 Ease of Doing Business With Average: 6.7 9.2 Ease of Setup Average: 7.7 8.4 Quality of Support Average: 9.2 8.9 Ease of Admin Average: 7.6 8.4 [Expand/Collapse Viedoc](#) #2 [![Viedoc](https://images.g2crowd.com/uploads/product/hd_favicon/10deb15544ce14a0f7747ee8ff8e0cdb/viedoc.svg)](/products/viedoc/reviews) [Viedoc](/products/viedoc/reviews "Viedoc") 74 [Expand/Collapse Viedoc](#) Overall Satisfaction Score 74 Top Industries of Reviewers: Pharmaceuticals 35% Research 32% Information Technology and Services 16% Medical Devices 16% Ratings from Reviews (out of 10): Ease of Use Average: 9.1 9.6 Meets Requirements Average: 9.4 9.4 Ease of Doing Business With Average: 6.7 10.0 Ease of Setup Average: 7.7 9.2 Quality of Support Average: 9.2 9.9 Ease of Admin Average: 7.6 8.9 [Expand/Collapse Egnyte](#) #3 [![Egnyte](https://images.g2crowd.com/uploads/product/hd_favicon/91bb854a397a0e939339a805a61acf75/egnyte.svg)](/products/egnyte/reviews) [Egnyte](/products/egnyte/reviews "Egnyte") 58 [Expand/Collapse Egnyte](#) Overall Satisfaction Score 58 Top Industries of Reviewers: Higher Education 36% Construction 27% Accounting 18% Hospital & Health Care 18% Ratings from Reviews (out of 10): Ease of Use Average: 9.1 9.8 Meets Requirements Average: 9.4 10.0 Ease of Doing Business With Average: 6.7 8.7 Ease of Setup Average: 7.7 10.0 Quality of Support Average: 9.2 9.7 Ease of Admin Average: 7.6 10.0 [Expand/Collapse Kivo](#) #4 [![Kivo](https://images.g2crowd.com/uploads/product/hd_favicon/8e78144ef1ecd54f15ff35b4d1fb6db5/kivo.svg)](/products/kivo/reviews) [Kivo](/products/kivo/reviews "Kivo") 46 [Expand/Collapse Kivo](#) Overall Satisfaction Score 46 Top Industries of Reviewers: Biotechnology 50% Pharmaceuticals 30% Hospital & Health Care 10% Consulting 10% Ratings from Reviews (out of 10): Ease of Use Average: 9.1 9.5 Meets Requirements Average: 9.4 9.9 Ease of Doing Business With Average: 6.7 10.0 Ease of Setup Average: 7.7 9.0 Quality of Support Average: 9.2 9.9 Ease of Admin Average: 7.6 9.5 [Expand/Collapse Clinical Research Suite](#) #5 [![Clinical Research Suite](https://images.g2crowd.com/uploads/product/hd_favicon/e340cf2d8162c8c01e4f2d519c48c10b/clinical-research-suite.svg)](/products/clinical-research-suite/reviews) [Clinical Research Suite](/products/clinical-research-suite/reviews "Clinical Research Suite") 30 [Expand/Collapse Clinical Research Suite](#) Overall Satisfaction Score 30 Top Industries of Reviewers: Hospital & Health Care 45% Medical Practice 24% Research 21% Mental Health Care 10% Ratings from Reviews (out of 10): Ease of Use Average: 9.1 8.1 Meets Requirements Average: 9.4 8.1 Ease of Doing Business With Average: 6.7 0.0 Ease of Setup Average: 7.7 8.3 Quality of Support Average: 9.2 7.7 Ease of Admin Average: 7.6 7.7 [Expand/Collapse Veeva Vault](#) #6 [![Veeva Vault](https://images.g2crowd.com/uploads/product/image/thumb_square/thumb_square_d567cc2d4c7229086852f8f5bc6a9b66/veeva-vault.png)](/products/veeva-vault/reviews) [Veeva Vault](/products/veeva-vault/reviews "Veeva Vault") 26 [Expand/Collapse Veeva Vault](#) Overall Satisfaction Score 26 Top Industries of Reviewers: Pharmaceuticals 59% Biotechnology 25% Hospital & Health Care 9% Marketing and Advertising 6% Ratings from Reviews (out of 10): Ease of Use Average: 9.1 8.8 Meets Requirements Average: 9.4 9.8 Ease of Doing Business With Average: 6.7 8.9 Ease of Setup Average: 7.7 9.3 Quality of Support Average: 9.2 8.8 Ease of Admin Average: 7.6 8.9 [Expand/Collapse ACE](#) #7 [![ACE](https://images.g2crowd.com/uploads/product/hd_favicon/970e78f805cb6e8e8b51d83124b86ee3/psc-software-ace.svg)](/products/psc-software-ace/reviews) [ACE](/products/psc-software-ace/reviews "ACE") 16 [Expand/Collapse ACE](#) Overall Satisfaction Score 16 Top Industries of Reviewers: Pharmaceuticals 50% Biotechnology 42% Consumer Goods 8% Ratings from Reviews (out of 10): Ease of Use Average: 9.1 9.8 Meets Requirements Average: 9.4 9.8 Ease of Doing Business With Average: 6.7 0.0 Ease of Setup Average: 7.7 0.0 Quality of Support Average: 9.2 9.8 Ease of Admin Average: 7.6 0.0